GANAB: A Potential Drug Target and Biomarker for Psychiatric Conditions

Target Name: GANAB

NCBI ID: G23193

GANAB: A Potential Drug Target and Biomarker for Psychiatric Conditions

GANAB (GANAB variant 2) is a protein that is expressed in the brain and has been shown to play a role in various neurological and psychiatric conditions, including depression, anxiety, and schizophrenia. While the exact function of GANAB is not yet fully understood, research has identified several potential drug targets and biomarkers that may be associated with this protein.

One of the primary drug targets for GANAB is its role in synaptic plasticity, which is the ability of the brain to change and adapt over time. GANAB has been shown to play a role in the regulation of synaptic plasticity, which may contribute to its potential as a drug target.

Another potential drug target for GANAB is its role in mood regulation. GANAB has been shown to be involved in the regulation of mood, and changes in GANAB levels have been linked to changes in mood. Therefore, drugs that target GANAB may have potential as antidepressants or antipsychotics.

In addition to its potential as a drug target, GANAB has also been identified as a potential biomarker for various psychiatric conditions. The levels of GANAB have been shown to be abnormal in individuals with depression, anxiety, and schizophrenia, which may suggest that these conditions are associated with changes in GANAB levels. Therefore, GANAB levels may be a potential biomarker for these conditions.

While more research is needed to fully understand the function of GANAB, its potential as a drug target and biomarker make it a promising target for future research. As such, GANAB is likely to continue to be a focus of research in the coming years, with the potential to revolutionize our understanding of various psychiatric and neurological conditions.

Protein Name: Glucosidase II Alpha Subunit

Functions: Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia (PubMed:27259053)

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