SNX33: A Protein Regulating Ion Channels and Cell Signaling (G257364)
SNX33: A Protein Regulating Ion Channels and Cell Signaling
SNX33 (SH3PX3) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the SH3PX family of proteins, which are known for their role in intracellular signaling.
One of the key functions of SNX33 is its role in the regulation of ion channels, which are responsible for the flow of electrical signals through cells. SNX33 helps to regulate the activity of these channels, which is important for a wide range of physiological processes, including muscle contractions, nerve signals, and the regulation of blood pressure.
SNX33 is also involved in the regulation of cell signaling pathways, which are the processes by which cells communicate with one another. It helps to regulate the activity of signaling pathways that are involved in cell growth, differentiation, and survival.
In addition to its role in cell signaling, SNX33 is also thought to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of inflammatory responses, and may be a potential target for the development of new treatments for a variety of inflammatory disorders.
SNX33 is also a potential drug target, as it has been shown to interact with a variety of different drugs, including some that are used to treat a wide range of psychiatric and neurological disorders. It is thought to be involved in the regulation of the activity of dopamine, a neurotransmitter that is involved in mood, motivation, and other aspects of brain function.
One of the challenges in studying SNX33 is its complex structure. While it is known to have several unique genetic variants, it is not clear how these variants contribute to its function. Further research is needed to fully understand the role of SNX33 in the regulation of ion channels and cell signaling pathways, as well as its potential as a drug target.
In conclusion, SNX33 is a protein that is expressed in various tissues of the body, and is involved in the regulation of ion channels, cell signaling pathways, and inflammation. It is a potential drug target, and further research is needed to fully understand its role in the regulation of cellular processes.
Protein Name: Sorting Nexin 33
Functions: Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes
More Common Targets
SNX4 | SNX5 | SNX6 | SNX7 | SNX8 | SNX9 | SOAT1 | SOAT2 | SOBP | SOCAR | SOCS1 | SOCS2 | SOCS2-AS1 | SOCS3 | SOCS3-DT | SOCS4 | SOCS5 | SOCS5P5 | SOCS6 | SOCS7 | SOD1 | SOD2 | SOD2-OT1 | SOD3 | Sodium channel | Sodium-Glucose Cotransporter (SGLT) | Sodium-potassium-calcium exchanger | SOGA1 | SOGA3 | SOHLH1 | SOHLH2 | Soluble (cytosolic) protein tyrosine phosphatases | Soluble guanylyl cyclase | Solute Carrier Family 12 | Solute carrier family 29 member | Somatostatin receptor | SON | SORBS1 | SORBS2 | SORBS3 | SORCS1 | SORCS2 | SORCS3 | SORCS3-AS1 | SORD | SORD2P | SORL1 | SORT1 | Sorting and assembly machinery complex | Sorting nexin | SOS1 | SOS2 | SOSS complex | SOST | SOSTDC1 | SOWAHA | SOWAHB | SOWAHC | SOWAHD | SOX1 | SOX1-OT | SOX10 | SOX11 | SOX12 | SOX13 | SOX14 | SOX15 | SOX17 | SOX18 | SOX2 | SOX2-OT | SOX21 | SOX21-AS1 | SOX3 | SOX30 | SOX30P1 | SOX4 | SOX5 | SOX5-AS1 | SOX6 | SOX7 | SOX8 | SOX9 | SOX9-AS1 | SP1 | SP100 | SP110 | SP140 | SP140L | SP2 | SP2-AS1 | SP3 | SP3P | SP4 | SP5 | SP6 | SP7 | SP8 | SP9 | SPA17
