L3MBTL1: Regulating Cellular Processes and Influencing PDZP and EGFR

Target Name: L3MBTL1

NCBI ID: G26013

L3MBTL1: Regulating Cellular Processes and Influencing PDZP and EGFR

L3MBTL1 (FLJ41181) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is a member of the L3MBTL1 family, which is characterized by the presence of a specific domain called L3MBT. This domain is known to be involved in the regulation of cellular processes, including cell adhesion, migration, and invasion.

One of the unique features of L3MBTL1 is its ability to interact with other proteins, particularly with the protein known as PDZP ( Postsynaptic density Zn2+-protein). This interaction between L3MBTL1 and PDZP is important for the function of the protein, as it allows L3MBTL1 to influence the activity of PDZP.

In addition to its interaction with PDZP, L3MBTL1 has also been shown to interact with several other proteins, including the protein known as EGFR (E Growth factor receptor). This interaction between L3MBTL1 and EGFR is important for the function of L3MBTL1, as it allows L3MBTL1 to influence the activity of EGFR.

EGFR is a transmembrane protein that is involved in the regulation of cell growth, angiogenesis, and survival. It is a receptor for several different proteins, including the protein known as tyrosine kinase inhibitors. These inhibitors are commonly used to treat various types of cancer, including breast, lung, and colorectal cancer.

The interaction between L3MBTL1 and EGFR is important for the function of L3MBTL1, as it allows L3MBTL1 to influence the activity of EGFR. This interaction between L3MBTL1 and EGFR is also important for the development of certain diseases, such as cancer.

In conclusion, L3MBTL1 is a protein that is expressed in various tissues of the human body. It is a member of the L3MBTL1 family and is characterized by the presence of a specific domain called L3MBT. L3MBTL1 has been shown to interact with several other proteins, including PDZP and EGFR. These interactions are important for the function of L3MBTL1 and are also important for the development of certain diseases. Further research is needed to fully understand the role of L3MBTL1 in the regulation of cellular processes and the development of disease.

Protein Name: L3MBTL Histone Methyl-lysine Binding Protein 1

Functions: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys-860'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis

More Common Targets