Late Cornified Envelope Protein 1C: A Potential Drug Target Or Biomarker

Target Name: LCE1C

NCBI ID: G353133

Late Cornified Envelope Protein 1C: A Potential Drug Target Or Biomarker

Late cornified envelope protein 1C (LCE1C) is a protein that is expressed in a variety of tissues in the body, including the liver, spleen, and muscle. It is a member of the late cornified envelope (LE) family of proteins, which are involved in the regulation of cellular processes such as cell adhesion and migration. LCE1C is of particular interest as a potential drug target or biomarker, due to its unique structure and biology.

Structure and Function

The LCE1C protein is a 180-kDa protein that is composed of 111 amino acid residues. It has a unique structure that is characterized by a long extracellular domain and a short intracellular domain. The extracellular domain of LCE1C is made up of a single伪-helix , which is followed by a long 尾-sheet that is responsible for the protein's stability and functions. The intracellular domain of LCE1C is made up of a 尾-strand that is involved in the protein's interactions with other cellular components.

LCE1C is involved in the regulation of cellular processes such as cell adhesion, migration, and signaling. It has been shown to play a role in the regulation of cell-cell adhesion, as well as the regulation of cell migration and the establishment of tissue boundaries . LCE1C is also involved in the regulation of cell signaling, including the regulation of cell proliferation and the modulation of cellular signaling pathways.

Drug Targeting and Biomarker Potential

The unique structure and biology of LCE1C make it an attractive target for drug development. Due to its ability to interact with a variety of cellular components, LCE1C has the potential to be a useful drug for the treatment of a wide range of diseases.

One potential mechanism by which LCE1C could be targeted is through its role in the regulation of cell adhesion. LCE1C has been shown to play a role in the regulation of cell-cell adhesion, and inhibition of LCE1C has been shown to be a potential therapeutic approach for diseases such as cancer, neurodegenerative diseases, and autoimmune diseases.

Another potential mechanism by which LCE1C could be targeted is through its role in the regulation of cell signaling. LCE1C has been shown to play a role in the regulation of cell signaling, including the regulation of cell proliferation and the modulation of cellular signaling pathways. In addition, LCE1C has been shown to interact with a variety of signaling proteins, including TGF-β, PDGF, and NF-kappa-B. Therefore, inhibition of LCE1C has been shown to be a potential therapeutic approach for diseases such as cancer, neurodegenerative diseases, and autoimmune diseases.

Expression and Measurement

LCE1C is expressed in a variety of tissues in the body, including the liver, spleen, and muscle. It is typically expressed at levels of 1-10% of total cellular protein in these tissues. Measurement of LCE1C expression is typically done using techniques such as Western blotting, immunofluorescence, and mass spectrometry. These techniques allow researchers to detect and quantify the expression of specific proteins in a variety of tissues and cellular samples.

Conclusion

Late cornified envelope protein 1C (LCE1C) is a unique protein that is expressed in a variety of tissues in the body. It has a unique structure and biology that makes it an attractive target for drug development. LCE1C is involved in the regulation of cellular processes such as cell adhesion, migration, and signaling, and has been shown to play a role in the regulation of

Protein Name: Late Cornified Envelope 1C

Functions: Precursors of the cornified envelope of the stratum corneum

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