LAMB1: A Protein with Potential as A Drug Target and Biomarker

Target Name: LAMB1

NCBI ID: G3912

LAMB1: A Protein with Potential as A Drug Target and Biomarker

LAMB1 (Longest-caliber Mediator) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is involved in the regulation of cell-cell interactions, as well as the formation of tight junctions between cells. LAMB1 has also been shown to play a role in the development and progression of various diseases, including cancer.

One of the most promising aspects of LAMB1 is its potential as a drug target. LAMB1 has been shown to be involved in the regulation of cell-cell interactions, which makes it a potential target for small molecules that can modulate these interactions. Additionally, LAMB1 has been shown to play a role in the formation of tight junctions between cells, which makes it a potential target for drugs that can modulate tight junction formation.

Recent studies have also shown that LAMB1 is involved in the regulation of various signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a potential target for drugs that can modulate its activity.

In addition to its potential as a drug target, LAMB1 is also a potential biomarker for various diseases. Its involvement in the regulation of cell-cell interactions and the formation of tight junctions makes it a potential target for drugs that can modulate these processes. Additionally, LAMB1 has been shown to be involved in the regulation of various signaling pathways, which makes it a potential target for drugs that can modulate these pathways.

Overall, LAMB1 is a protein that has significant potential as a drug target and biomarker. Its involvement in the regulation of cell-cell interactions and the formation of tight junctions makes it a potential target for small molecules that can modulate these processes. Additionally, its involvement in the regulation of various signaling pathways makes it a potential target for drugs that can modulate these pathways. Further research is needed to fully understand the role of LAMB1 in these processes and to develop effective treatments for diseases that are caused by its dysfunction.

Protein Name: Laminin Subunit Beta 1

Functions: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface

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