Understanding LARP4: A Potential Drug Target (G113251)

Target Name: LARP4

NCBI ID: G113251

Understanding LARP4: A Potential Drug Target

LARP4 (LARP4 variant 4) is a protein that is expressed in various tissues of the body, including the brain, heart, and lungs. It is a member of the LARP4 family, which is characterized by the presence of a unique N-terminal domain called NXXL. The NXXL domain is known to play a crucial role in the regulation of cellular processes, including cell adhesion, migration, and survival.

One of the unique features of LARP4 is its ability to form inclusion bodies in response to various stimuli, such as bacterial toxins or viruses. These inclusion bodies are thought to be a mechanism by which LARP4 can contribute to the immune response and may be a potential drug target.

In addition to its role in the immune system, LARP4 has also been shown to be involved in several other cellular processes. For example, it has been shown to play a role in cell signaling, including the regulation of cell proliferation and the assembly of signaling pathways. It has also been shown to be involved in the regulation of cellular transport, including the transport of molecules across cell membranes.

Despite its potential role in several cellular processes, LARP4 is not well understood at the molecular level. There are currently few studies that have focused specifically on LARP4, and much of the research on this protein is still in its early stages. However, due to its unique structure and the interest in its role in various cellular processes, LARP4 is a promising candidate for further research and potential drug development.

In conclusion, LARP4 is a protein that has the potential to be a drug target due to its unique structure and its involvement in various cellular processes. Further research is needed to fully understand its role in the immune system and other cellular processes, and to explore its potential as a drug.

Protein Name: La Ribonucleoprotein 4

Functions: RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744)

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