Understanding The Function of CYP4X1A9 (G260293)

Target Name: CYP4X1

NCBI ID: G260293

Understanding The Function of CYP4X1A9

CYP4X1 (Cytochrome P450 family 4 subfamily X member 1) is a gene that encodes a protein known as CYP4X1A9. This gene is a member of the cytochrome P450 (CYP) gene family, which is a superfamily of enzymes that are involved in the metabolism of a wide variety of drugs and other molecules. CYP4X1A9 is one of the genes within the CYP4X1 subfamily, which is responsible for encoding the 9-carbon precursors of the cytochrome P450 enzyme.

The CYP4X1A9 gene is located on chromosome 19 at position 6.1 kb. It is a single exon gene that encodes a protein of 64 amino acids in length. The protein encoded by this gene is a member of the cytoplasmic side of the cell membrane, and it is involved in various cellular processes, including the metabolism of drugs and other molecules.

One of the key functions of CYP4X1A9 is its role in the metabolism of drugs. Many drugs work by altering the levels of certain metabolites in the body, and CYP4X1A9 is involved in the conversion of these metabolites into their active forms. This is important because drugs can have a wide range of effects on the body, and the levels of their metabolites can have a significant impact on their efficacy or potential for adverse effects.

Another function of CYP4X1A9 is its role in cellular signaling. The cytochrome P450 enzyme is involved in a variety of cellular signaling pathways, including the regulation of gene expression, cell signaling, and inflammation. CYP4X1A9 is involved in these signaling pathways by metabolizing various signaling molecules , including hormones and neurotransmitters.

In addition to its role in cellular signaling and drug metabolism, CYP4X1A9 is also involved in the regulation of cellular processes such as cell growth, apoptosis, and inflammation. These processes are important for maintaining the health and integrity of the body, and CYP4X1A9 is involved in regulating them.

Gene editing technologies such as CRISPR/Cas9 have the potential to study the function of CYP4X1A9 and its role in various cellular processes. By modifying the CYP4X1A9 gene, researchers can gain a better understanding of its function and how it contributes to the development and progression of various diseases.

In conclusion, CYP4X1A9 is a gene that encodes a protein involved in various cellular processes, including drug metabolism and signaling. Its function is likely to be a drug target or biomarker, and research into its role in the development and progression of various diseases may have important implications for the development of new treatments.

Protein Name: Cytochrome P450 Family 4 Subfamily X Member 1

Functions: A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)

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