ARHGEF26: Key Regulator of HGF Signaling and Cellular Processes

Target Name: ARHGEF26

NCBI ID: G26084

ARHGEF26: Key Regulator of HGF Signaling and Cellular Processes

ARHGEF26 (SH3 domain-containing guanine exchange factor) is a protein that plays a critical role in cell signaling pathways. It is a key regulator of the Hedgehog (HGF) signaling pathway, which is involved in many cellular processes, including tissue repair, cell proliferation, and development.

The HGF signaling pathway is a complex pathway that involves the interaction of multiple proteins, including ARHGEF26. This protein is a key regulator of the HGF signaling pathway, and it is involved in the regulation of many cellular processes.

One of the key functions of ARHGEF26 is its role as a guanine exchange factor. This protein is able to transfer guanine atoms between two proteins, which is a critical process in the regulation of protein-protein interactions.

ARHGEF26 is a member of the SH3 domain family, which is a family of proteins that are characterized by the presence of a single transmembrane domain and a unique ATP-binding site. This domain is responsible for the protein's ability to interact with its target proteins and for the regulation of its function.

ARHGEF26 is involved in many cellular processes, including the regulation of cell proliferation, differentiation, and survival. It is a key regulator of the HGF signaling pathway, which is involved in the regulation of many cellular processes.

ARHGEF26 is also involved in the regulation of many cellular processes, including the regulation of cell adhesion, migration, and the formation of tissues. It is a key regulator of the Wnt signaling pathway, which is involved in the regulation of cell growth and differentiation.

ARHGEF26 is also involved in the regulation of many cellular processes, including the regulation of cell signaling pathways, including the regulation of the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival.

ARHGEF26 is a key regulator of the HGF signaling pathway, which is involved in the regulation of many cellular processes. It is also involved in the regulation of many cellular processes, including the regulation of cell adhesion, migration, and the formation of tissues.

In conclusion, ARHGEF26 is a protein that plays a critical role in cell signaling pathways. It is a key regulator of the HGF signaling pathway and is involved in the regulation of many cellular processes, including the regulation of cell adhesion, migration, and the formation of tissues.

ARHGEF26 may be a drug target or biomarker due to its involvement in the regulation of cellular processes and its role as a guanine exchange factor. Further research is needed to fully understand the role of ARHGEF26 in cell signaling pathways and its potential as a drug target or biomarker.

Protein Name: Rho Guanine Nucleotide Exchange Factor 26

Functions: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry

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