ARL11: Protein At The Center of Cell Signaling and Survival (G115761)

Target Name: ARL11

NCBI ID: G115761

ARL11: Protein At The Center of Cell Signaling and Survival

ARL11 (MGC17429) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ARL family of proteins, which are involved in the regulation of cell survival and growth. ARL11 has been shown to play a role in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, it has become a focus of interest for researchers looking for new potential drug targets or biomarkers.

One of the key features of ARL11 is its ability to interact with a variety of different molecules. This allows it to play a role in a wide range of cellular processes, including cell signaling, cell division, and cell survival. ARL11 has been shown to interact with a variety of different proteins, including TGF-β1, PDGF, and NF-kappa-B. These interactions can modulate the activity of these molecules, which in turn can affect the behavior of the cells.

One of the ways that ARL11 interacts with other molecules is through its role in the regulation of the actin cytoskeleton. The actin cytoskeleton is the network of filaments that makes up the structure of the cell. It is involved in many different cellular processes, including cell movement, the distribution of organelles, and the regulation of the cell cycle. ARL11 is known to play a role in the regulation of the actin cytoskeleton by interacting with the protein F-actin. This interaction can modulate the activity of F-actin, which in turn can affect the stability of the actin cytoskeleton.

Another way that ARL11 interacts with other molecules is through its role in the regulation of cell survival. Cell survival is a critical aspect of life, and it is regulated by a wide range of different factors. ARL11 is known to play a role in the regulation of cell survival by interacting with the protein Bcl-2. This interaction can modulate the activity of Bcl-2, which in turn can affect the ability of cells to survive in various environments.

In addition to its role in cell signaling and survival, ARL11 has also been shown to play a role in the regulation of cell division. During cell division, ARL11 is involved in the formation of the chromatin fiber network, which is the structure that makes up the chromosomes. This interaction can modulate the activity of the protein components, which in turn can affect the stability of the chromatin fiber network.

Overall, ARL11 is a protein that has a wide range of interactions with other molecules. These interactions can modulate the activity of these molecules, which in turn can affect a wide range of cellular processes. As a result, ARL11 has become a focus of interest for researchers looking for new potential drug targets or biomarkers. Further research is needed to fully understand the role of ARL11 in cellular processes, and to develop new treatments for diseases that are caused by its dysfunction.

Protein Name: ADP Ribosylation Factor Like GTPase 11

Functions: May play a role in apoptosis. May act as a tumor suppressor

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