ARRDC5: Key Regulator of Cell Cycle and Actin Cytoskeleton (G645432)

Target Name: ARRDC5

NCBI ID: G645432

ARRDC5: Key Regulator of Cell Cycle and Actin Cytoskeleton

Arrestin domain-containing protein 5 (ARRDC5) is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and heart. It is a key regulator of the cell cycle, and has been implicated in a number of diseases , including cancer, neurodegenerative diseases, and autoimmune disorders.

ARRDC5 is a protein that is composed of three domains: an N-terminal alpha-helix, a middle beta-sheet, and an C-terminal T-loop. The N-terminal domain contains a unique aromatic amino acid residue, known as tryptophan , which is involved in the formation of a distinct protein-protein interaction network. The middle beta-sheet contains several conserved amino acids that are involved in the formation of the protein structure and are highly conserved across different species. The C-terminal domain contains a unique amino acid residue, known as Asp-212, which is involved in the regulation of protein stability and dynamics.

ARRDC5 is a key regulator of the cell cycle, and is involved in the G1, S, G2, and G0 phases of the cell cycle. It is a positive regulator of the G1 phase, and is involved in the progression of cells through the G1 phase. It is also a negative regulator of the S phase, and is involved in the inhibition of cell proliferation.

ARRDC5 is also involved in the regulation of the actin cytoskeleton. It is a positive regulator of actin filament formation, and is involved in the regulation of actin dynamics and stability. It is also involved in the regulation of the interaction between actin and the cytoskeleton.

ARRDC5 is a potential drug target for a number of diseases. It is involved in the regulation of the cell cycle, which is a key factor in the development and progression of cancer. It is also involved in the regulation of actin cytoskeleton, which is a key factor in the regulation of muscle strength and function.

ARRDC5 is also involved in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It is a potential drug target for these diseases, as it is involved in the regulation of the cell cycle and the actin cytoskeleton, which are key factors in the development and progression of these diseases.

ARRDC5 is also involved in the regulation of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. It is a potential drug target for these diseases, as it is involved in the regulation of the cell cycle and the actin cytoskeleton, which are key factors in the development and progression of these diseases.

In conclusion, Arrestin domain-containing protein 5 (ARRDC5) is a protein that is involved in a number of important biological processes in the cell. It is a key regulator of the cell cycle, and is involved in the regulation of the cell cycle, actin cytoskeleton, and neurodegenerative diseases. It is a potential drug target for a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of Arrestin domain-containing protein 5 in these diseases, and to develop effective therapies for the treatment of these conditions.

Protein Name: Arrestin Domain Containing 5

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