ASPH2: A Protein Involved in BBB, Inflammation and Fibrosis (G57168)

Target Name: ASPHD2

NCBI ID: G57168

Other Name(s): ASPH2_HUMAN | FLJ39838 | Aspartate beta-hydroxylase domain-containing protein 2 | aspartate beta-hydroxylase domain containing 2 | Aspartate beta-hydroxylase domain containing 2

ASPH2: A Protein Involved in BBB, Inflammation and Fibrosis

ASPHD2 (ASPH2_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and muscle. It is a member of the ASPH2 family, which is known for their role in the development and maintenance of blood-brain barrier (BBB) integrity. The BBB is a specialized barrier that separates the brain from the surrounding bloodstream, and it is designed to protect the brain from harmful substances that could cause injury or disease.

ASPH2 is known for its role in the regulation of cell-cell and cell-tissue interactions, as well as its role in the development and maintenance of the BBB. It is also involved in the regulation of inflammation and fibrosis.

ASPH2 has been shown to be involved in a number of diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune diseases. It is also a potential drug target for a number of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the key challenges in studying ASPH2 is its high level of expression in a wide range of tissues, making it difficult to study its effects in specific organs or conditions. However, research into its role in the regulation of the BBB and its potential as a drug target is ongoing.

ASPH2 has been shown to play a role in the regulation of the BBB. Studies have shown that ASPH2 is involved in the formation of the BBB, as well as its maintenance and regulation. This suggests that ASPH2 may be a useful target for drugs that are designed to modulate the BBB.

In addition to its role in the BBB, ASPH2 is also involved in the regulation of inflammation and fibrosis. Studies have shown that ASPH2 is involved in the regulation of immune cell function, as well as the production of pro-inflammatory cytokines. This suggests that ASPH2 may be a useful target for drugs that are designed to prevent or alleviate inflammation and fibrosis.

ASPH2 has also been shown to be involved in the regulation of cell-cell and cell-tissue interactions. Studies have shown that ASPH2 is involved in the regulation of cell-cell adhesion, as well as the formation of tight junctions between cells. This suggests that ASPH2 may be a useful target for drugs that are designed to modulate cell-cell interactions.

In conclusion, ASPH2 is a protein that is involved in a wide range of physiological processes in the human body. Its role in the regulation of the BBB, inflammation, and fibrosis makes it a potential drug target for a number of diseases. Further research is needed to fully understand the effects of ASPH2 and its potential as a drug.

Protein Name: Aspartate Beta-hydroxylase Domain Containing 2

Functions: May function as 2-oxoglutarate-dependent dioxygenase

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