ATL3: A Protein Involved in Cellular Processes and Potential Drug Target

Target Name: ATL3

NCBI ID: G25923

ATL3: A Protein Involved in Cellular Processes and Potential Drug Target

ATL3 (ATP-thioredoxinase 3) is a protein that is expressed in various cell types of the human body. It is a member of the ATP-thioredoxinase family, which is a group of proteins that are involved in the regulation of cellular processes such as cell growth, apoptosis, and metabolism. The function of ATL3 is to regulate the activity of ATP, which is a crucial energy source for the cell.

ATL3 is a 21-kDa protein that is expressed in various tissues of the body, including the brain, heart, liver, and muscle. It is mainly localized to the endoplasmic reticulum (ER), which is the protein synthesis and modification system that retrieves and modifies proteins before they are transported to the plasma membrane for export.

ATL3 is a key regulator of the activity of the enzyme GTPase3, which is a type of ATP-dependent protein kinase that is involved in various cellular processes, including cell signaling, cell division, and protein synthesis. The activity of GTPase3 is regulated by ATL3 , which interacts with the protein GDP-GTP and activates the protein to perform its function.

ATL3 functions as a negative regulator of GTPase3 by inhibiting its activity. This interaction between ATL3 and GTPase3 is critical for the regulation of cellular processes, including the regulation of cell growth, apoptosis, and metabolism.

ATL3 is also involved in the regulation of cellular signaling pathways, including the TGF-β pathway. TGF-β is a cytokine that plays a crucial role in the regulation of cellular processes, including cell growth, apoptosis, and differentiation. pathway is a complex signaling pathway that is involved in the regulation of cellular processes, including cell signaling, cell growth, and apoptosis.

ATL3 is a key regulator of the activity of the protein FGF1, which is a cytokine that plays a crucial role in the regulation of cellular processes, including cell growth, apoptosis, and differentiation. The FGF1 signaling pathway is involved in the regulation of cellular processes , including the regulation of cell signaling, cell growth, and apoptosis.

ATL3 is also involved in the regulation of cellular processes that are critical for the development and maintenance of tissues. For example, ATL3 is involved in the regulation of cell proliferation, which is critical for the development and maintenance of tissues.

ATL3 is a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. The inhibition of ATL3 activity has been shown to have therapeutic benefits in various models of disease, including cancer, neurodegenerative diseases, and cardiovascular diseases.

Conclusion

ATL3 is a protein that is involved in the regulation of various cellular processes that are critical for the development and maintenance of tissues. It is a key regulator of the activity of the enzyme GTPase3 and the protein FGF1, and it is involved in the regulation of cell proliferation. The inhibition of ATL3 activity has been shown to have therapeutic benefits in various models of disease, including cancer, neurodegenerative diseases, and cardiovascular diseases. Therefore, ATL3 is a potential drug target and biomarker for various diseases.

Protein Name: Atlastin GTPase 3

Functions: GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:18270207, PubMed:19665976, PubMed:27619977)

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