ATP10D: A Potential Drug Target for Neurological Disorders (G57205)

Target Name: ATP10D

NCBI ID: G57205

ATP10D: A Potential Drug Target for Neurological Disorders

ATP10D (AT10D_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and skeletal muscles. It is a key regulator of the protein ATP10, which is involved in a variety of cellular processes, including muscle contractions and protein synthesis.

Recent studies have identified ATP10D as a potential drug target or biomarker for a variety of neurological and cardiovascular diseases, including Alzheimer's disease, Parkinson's disease, and myocardial infarction.

One of the reasons for the interest in ATP10D is its role in the regulation of muscle contractions. Muscle contractions are critical for maintaining posture, movement, and other activities that require strength and coordination. The protein ATP10 is involved in the regulation of muscle contractions by controlling the release of calcium ions, which are essential for muscle relaxation and muscle contractions.

In individuals with Alzheimer's disease, muscle contractions can become abnormally regulated, leading to a range of symptoms, including tremors, stiffness, and difficulty with movement. By targeting the regulation of muscle contractions by ATP10D, researchers may be able to develop new treatments for Alzheimer's disease and other neurological disorders.

ATP10D is also involved in the regulation of protein synthesis, which is the process by which the cell builds and repairs its proteins. In diseases such as cancer, disruptions in protein synthesis can lead to the rapid growth and progression of the disease. By targeting ATP10D, researchers may be able to develop new treatments for a variety of cancers.

In addition to its role in muscle and protein synthesis regulation, ATP10D is also involved in the regulation of cell signaling pathways. In diseases such as heart disease, disruptions in cell signaling can lead to the development of new technologies for treating these conditions. By targeting ATP10D, researchers may be able to develop new treatments for heart disease and other cardiovascular disorders.

Overall, ATP10D is a protein that has the potential to be a drug target or biomarker for a variety of neurological and cardiovascular diseases. Further research is needed to fully understand its role and potential clinical applications.

Protein Name: ATPase Phospholipid Transporting 10D (putative)

Functions: Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of the plasma membrane

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