Target Name: ASB13
NCBI ID: G79754
Other Name(s): FLJ13134 | MGC19879 | ASB13_HUMAN | ASB-13 | Ankyrin repeat domain-containing SOCS box protein Asb-13 | Ankyrin repeat and SOCS box protein 13 | Ankyrin repeat and SOCS box-containing 13 | Ankyrin repeat and SOCS box containing 13, transcript variant 1 | ankyrin repeat and SOCS box containing 13 | ASB13 variant 1 | ankyrin repeat domain-containing SOCS box protein Asb-13

Understanding The Role of ASB13 in Disease

ASB13 (FLJ13134) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ASB family of proteins, which are known for their role in intracellular signaling.

ASB13 is involved in a variety of physiological processes in the body, including the regulation of ion channels, neurotransmitter signaling, and cell survival. It has been shown to play a role in a variety of diseases, including neurodegenerative disorders, neuroimmune diseases, and cardiovascular diseases disease.

One of the ASB13 functions is to regulate the activity of ion channels, which are proteins that allow or block the flow of electrical currents through cells. ASB13 is known to interact with a variety of ion channels, including the Na+, K+, and Ca2+ channels.

ASB13 has been shown to play a role in the regulation of neuronal excitability and synaptic plasticity. Studies have shown that ASB13 interacts with the neurotransmitter glutamate, which is a signaling molecule in the brain. This interaction may play a role in the regulation of neuronal excitability and synaptic plasticity.

ASB13 is also involved in the regulation of cell survival. Studies have shown that ASB13 can interact with a variety of cellular signaling pathways, including the TGF-β pathway. This interaction may play a role in the regulation of cell survival and the response to stress.

ASB13 has also been shown to be involved in the regulation of inflammation. Studies have shown that ASB13 can interact with the chemokine receptor, PDGF receptor, and NF-kappa-B signaling pathway. This interaction may play a role in the regulation of inflammation and the response to infection.

Despite the many functions of ASB13, little is known about its specific role in any one disease. Further research is needed to fully understand the role of ASB13 in disease and to identify potential drug targets.

In conclusion, ASB13 is a protein that is involved in a variety of physiological processes in the body. Its functions include the regulation of ion channels, neurotransmitter signaling, cell survival, and inflammation. Further research is needed to fully understand the role of ASB13 in disease and to identify potential drug targets.

Protein Name: Ankyrin Repeat And SOCS Box Containing 13

Functions: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

More Common Targets

ASB14 | ASB15 | ASB16 | ASB16-AS1 | ASB17 | ASB18 | ASB2 | ASB3 | ASB4 | ASB5 | ASB6 | ASB7 | ASB8 | ASB9 | ASB9P1 | ASCC1 | ASCC2 | ASCC3 | ASCL1 | ASCL3 | ASCL4 | ASCL5 | ASF1A | ASF1B | ASGR1 | ASGR2 | ASH1L | ASH1L-AS1 | ASH2L | Asialoglycoprotein receptor | Asialoglycoprotein Receptor (ASGPR) | ASIC1 | ASIC2 | ASIC3 | ASIC4 | ASIC5 | ASIP | ASL | ASMER1 | ASMER2 | ASMT | ASMTL | ASMTL-AS1 | ASNS | ASNSD1 | ASNSP1 | ASPA | ASPDH | ASPG | ASPH | ASPHD1 | ASPHD2 | ASPM | ASPN | ASPRV1 | ASPSCR1 | ASRGL1 | ASS1 | ASS1P1 | ASS1P10 | ASS1P11 | ASS1P12 | ASS1P13 | ASS1P2 | ASS1P4 | ASS1P5 | ASS1P6 | ASS1P7 | ASS1P9 | ASTE1 | ASTL | ASTN1 | ASTN2 | ASTN2-AS1 | Astrin complex | ASXL1 | ASXL2 | ASXL3 | ASZ1 | AT-Rich interactive domain-containing protein | ATAD1 | ATAD2 | ATAD2B | ATAD3A | ATAD3B | ATAD3C | ATAD5 | ATAT1 | ATCAY | ATE1 | ATE1-AS1 | ATF1 | ATF2 | ATF3 | ATF4 | ATF4P2 | ATF4P4 | ATF5 | ATF6 | ATF6-DT