ASPA: A Potential Drug Target for Type 2 Diabetes (G443)

Target Name: ASPA

NCBI ID: G443

ASPA: A Potential Drug Target for Type 2 Diabetes

ASPA (Aminoacylase 2) is a protein that is expressed in various tissues throughout the body, including the liver, pancreas, and muscle. It is a key enzyme that is involved in the metabolism of a type of sugar called alpha-glucose, which is a major fuel source for the body.

In individuals with type 2 diabetes, the body's ability to produce and use insulin is impaired, leading to high levels of glucose in the blood. This can cause a wide range of health problems, including heart attacks, strokes, and complications such as diabetic ketoacidosis.

ASPA plays a key role in the breakdown of alpha-glucose and the production of insulin. In studies, ASPA has been shown to be a potential drug target for the treatment of type 2 diabetes. By inhibiting the activity of ASPA, researchers hope to improve insulin sensitivity and increase the body's ability to use insulin.

ASPA is also a potential biomarker for the diagnosis and monitoring of type 2 diabetes. The level of ASPA in the body can be affected by various factors, including diet, exercise, and stress. By measuring the level of ASPA in the body, researchers can track the effectiveness of different treatments and monitor for potential complications.

ASPA is also involved in the regulation of cellular processes in the body, including cell signaling and metabolism. It has been shown to play a role in the development and progression of various diseases, including cancer.

ASPA is a protein that is expressed in various tissues throughout the body, and it is involved in the metabolism of alpha-glucose. It is a potential drug target for the treatment of type 2 diabetes, and it is also a potential biomarker for the diagnosis and monitoring of this disease.

Protein Name: Aspartoacylase

Functions: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids

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