ASPH Variant 6: Potential Drug Target for Neurodegenerative Disorders and Cancer

Target Name: ASPH

NCBI ID: G444

ASPH Variant 6: Potential Drug Target for Neurodegenerative Disorders and Cancer

ASPH (ASPH variant 6) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and endothelial cells. It is a member of the ASPH family, which is known for its role in the regulation of cell survival and proliferation.

ASPH variant 6 is a 21-kDa protein that is expressed in the brain, heart, and kidneys. It is highly expressed in the brain, where it is found in the basal ganglia, which is responsible for the coordination of motor movement. It is also found in the heart, where it is involved in the regulation of contractility and heart rate. In the kidneys, it is involved in the regulation of water and electrolyte balance.

ASPH variant 6 has been shown to play a role in the regulation of cell survival and proliferation. It has been shown to promote the survival of brain cells by increasing the levels of a protein called Bcl-2. Bcl-2 is a protein that has been shown to promote the survival of many types of cells, including brain cells.

ASPH variant 6 has also been shown to play a role in the regulation of cell signaling. It is a member of the ASPH family, which is known for its role in the regulation of cell signaling. It is thought to function as a negative regulator of the signaling pathway known as the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival.

ASPH variant 6 is also a potential drug target. Because it is involved in the regulation of cell survival and proliferation, it is a potential target for drugs that are designed to promote cell death or to inhibit cell growth. This could make it a useful target for the treatment of various diseases, including neurodegenerative disorders and cancer.

In conclusion, ASPH variant 6 is a protein that is expressed in various tissues throughout the body and is involved in the regulation of cell survival and proliferation. It is a member of the ASPH family and has been shown to play a role in the regulation of cell signaling and the regulation of cell death. As a potential drug target, it is a promising target for the treatment of various diseases. Further research is needed to fully understand the role of ASPH variant 6 in the regulation of cell behavior and to develop effective treatments.

Protein Name: Aspartate Beta-hydroxylase

Functions: Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins

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