ARL9 Interacts with Tau, FAK and Neurodegeneration (G132946)
ARL9 Interacts with Tau, FAK and Neurodegeneration
ARL9 (ARL9 variant 2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ARL family of proteins, which are known for their role in regulating the blood-brain barrier. The ARL9 protein has been shown to play a role in a variety of physiological processes, including the regulation of inflammation, neurodegeneration, and stress.
One of the unique features of ARL9 is its ability to interact with a variety of different proteins, including the protein known as Tau. Tau is a protein that is involved in the formation of beta-amyloid plaques, which are a hallmark of Alzheimer's disease. The interaction between ARL9 and Tau has been shown to play a role in the development and progression of this disease.
In addition to its role in the regulation of the blood-brain barrier, ARL9 has also been shown to play a role in the regulation of inflammation. Inflammation is a complex process that is involved in the immune response and can contribute to a variety of diseases, including heart disease and neurodegeneration. The interaction between ARL9 and inflammation has been shown to play a role in the regulation of these processes.
Another unique feature of ARL9 is its ability to interact with the protein known as FAK. FAK is a protein that is involved in the regulation of cell-cell adhesion, and has been shown to play a role in a variety of diseases, including cancer. The interaction between ARL9 and FAK has been shown to play a role in the regulation of these processes.
In addition to its role in the regulation of the blood-brain barrier, ARL9 has also been shown to play a role in the regulation of neurodegeneration. Neurodegeneration is a process that is involved in the gradual loss of brain cells, and is a hallmark of various neurological diseases, including Alzheimer's disease. The interaction between ARL9 and neurodegeneration has been shown to play a role in the regulation of these processes.
In conclusion, ARL9 (ARL9 variant 2) is a protein that is expressed in various tissues of the body and is involved in a variety of physiological processes. The interaction between ARL9 and Tau, FAK, and neurodegeneration has been shown to play a role in the development and progression of various diseases, including Alzheimer's disease. Therefore, ARL9 may be a drug target or biomarker for the treatment of these diseases.
Protein Name: ADP Ribosylation Factor Like GTPase 9
More Common Targets
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