ARPC5L Subunit: Key Component of Arp2/3 Complex and Potential Drug Target

Target Name: ARPC5L

NCBI ID: G81873

ARPC5L Subunit: Key Component of Arp2/3 Complex and Potential Drug Target

Arp2/3 complex 16 kDa subunit 2 (ARPC5L) is a protein that plays a crucial role in the process of cell signaling, particularly in the regulation of cell adhesion and migration. The ARPC5L subunit is a key component of the Arp2/3 complex, which is a complex that regulates the delivery of vesicles from the endoplasmic reticulum (ER) to the cell surface. The ARPC5L subunit is composed of two transmembrane domains and a cytoplasmic tail, and its cytoplasmic tail is involved in the formation of the ARPC5L complex.

The ARPC5L subunit is expressed in most tissues and cells and is involved in various cellular processes, including cell adhesion, migration, and the regulation of cell signaling pathways. The ARPC5L subunit is also a potent drug target and has been identified as a potential therapeutic target for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

The ARPC5L subunit is involved in the regulation of the delivery of vesicles from the ER to the cell surface. Vesicles are small structures that emerge from the ER and are involved in the transport of various proteins to the cell surface. The ARPC5L subunit is part of the Arp2/3 complex, which is responsible for regulating the delivery of vesicles to the cell surface. The Arp2/3 complex is composed of the ARPC5L subunit, the protein p120Gap, and the protein p120Rho.

The ARPC5L subunit plays a crucial role in the regulation of cell adhesion and migration. During cell division, the ARPC5L subunit is involved in the formation of tight junctions, which are a type of cell-cell adhesion structure that helps to maintain the integrity of the cell membrane. The ARPC5L subunit is also involved in the regulation of cell migration, which is the movement of cells towards a specific direction.

The ARPC5L subunit is also involved in the regulation of cell signaling pathways. The ARPC5L subunit is a key component of the ARP2/3 complex, which is responsible for regulating the delivery of intracellular signaling molecules to the plasma membrane. The ARPC5L subunit is involved in the regulation of several signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway.

The ARPC5L subunit is a potent drug target and has been identified as a potential therapeutic target for various diseases. The ARPC5L subunit is a potential drug target because of its involvement in several cellular processes that are important for the development and progression of diseases. The ARPC5L subunit is a potential drug target for cancer, neurodegenerative diseases, and autoimmune diseases.

In conclusion, the ARPC5L subunit is a protein that plays a crucial role in the process of cell signaling, particularly in the regulation of cell adhesion and migration. The ARPC5L subunit is a key component of the Arp2/3 complex and is involved in various cellular processes that are important for the development and progression of diseases. The ARPC5L subunit is a potential drug target and has been identified as a potential therapeutic target for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Further research is needed to fully understand the role of the ARPC5L subunit in cell signaling and its potential as a drug target.

Protein Name: Actin Related Protein 2/3 Complex Subunit 5 Like

Functions: May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

More Common Targets