OXGR1: A GPCR Involved in Various Physiological Processes (G27199)
OXGR1: A GPCR Involved in Various Physiological Processes
OXGR1 (P2RY15), a protein encoded by the gene P2RY15, is a G protein-coupled receptor (GPCR) that plays a crucial role in various physiological processes in the body. It is a member of the P2Y family of GPCRs, which are a subclass of GPCRs that are involved in modulation of cellular responses to extracellular stimuli, including neurotransmitters and other signaling molecules.
OXGR1 is a key regulator of neuronal excitability and plays a critical role in the function of the nervous system. It is expressed in a variety of tissues, including the brain, spinal cord, and peripheral nerves, and is involved in the regulation of pain, inflammation, and neurotransmission.
One of the key functions of OXGR1 is its role in modulating neurotransmitter release from neurons. OXGR1 is involved in the regulation of neurotransmitter release from dopamine-producing neurons, and is thought to play a role in the development of Parkinson's disease.
In addition to its role in modulating neurotransmission, OXGR1 is also involved in the regulation of pain perception and inflammation. It is expressed in pain-sensitive neurons and is involved in the regulation of pain sensitivity. OXGR1 is also involved in the regulation of inflammation, and is thought to play a role in the regulation of chronic pain.
Another function of OXGR1 is its role in the regulation of cell survival. OXGR1 is involved in the regulation of cell survival and is thought to play a role in the development of neurodegenerative diseases.
OXGR1 is also involved in the regulation of sensory perception and in the regulation of the nervous system. It is expressed in neurons that are involved in the regulation of sensory perception and is involved in the regulation of the nervous system.
In conclusion, OXGR1 (P2RY15) is a protein that plays a critical role in various physiological processes in the body. It is a member of the P2Y family of GPCRs and is involved in the regulation of neuronal excitability, neurotransmission, pain perception, inflammation, and cell survival. Therefore, OXGR1 is a potential drug target and may be useful in the development of new treatments for a variety of neurodegenerative diseases.
Protein Name: Oxoglutarate Receptor 1
Functions: Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity)
More Common Targets
OXLD1 | OXNAD1 | OXR1 | OXSM | OXSR1 | OXT | OXTR | Oxysterol-binding protein | Oxysterols receptor LXR | P2RX1 | P2RX2 | P2RX3 | P2RX4 | P2RX5 | P2RX5-TAX1BP3 | P2RX6 | P2RX6P | P2RX7 | P2RY1 | P2RY10 | P2RY10BP | P2RY11 | P2RY12 | P2RY13 | P2RY14 | P2RY2 | P2RY4 | P2RY6 | P2RY8 | P2X Receptor | P2Y purinoceptor | P3H1 | P3H2 | P3H3 | P3H4 | P3R3URF-PIK3R3 | P4HA1 | P4HA2 | P4HA3 | P4HB | P4HTM | PA28 Complex | PA28gamma Complex | PA2G4 | PA2G4P1 | PA2G4P4 | PAAF1 | PABIR1 | PABIR2 | PABIR3 | PABP-dependent poly(A) nuclease (PAN) complex | PABPC1 | PABPC1L | PABPC1L2A | PABPC1L2B | PABPC1P10 | PABPC1P2 | PABPC1P4 | PABPC1P7 | PABPC3 | PABPC4 | PABPC4-AS1 | PABPC4L | PABPC5 | PABPN1 | PABPN1L | PACC1 | PACERR | PACRG | PACRG-AS2 | PACRGL | PACS1 | PACS2 | PACSIN1 | PACSIN2 | PACSIN3 | PADI1 | PADI2 | PADI3 | PADI4 | PADI6 | PAEP | PAEPP1 | PAF1 | PAF1 complex | PAFAH1B1 | PAFAH1B2 | PAFAH1B2P2 | PAFAH1B3 | PAFAH2 | PAG1 | PAGE1 | PAGE2 | PAGE2B | PAGE3 | PAGE4 | PAGE5 | PAGR1 | PAH | PAICS