Targeting P2Y(cyc) for Therapeutic Applications in Pain and Neurotransmission
Targeting P2Y(cyc) for Therapeutic Applications in Pain and Neurotransmission
P2Y(cyc), also known as P2Y12, is a G protein-coupled receptor (GPCR) that plays a crucial role in pain modulation, neuropeptide signaling, and neurotransmission. It is a member of the P2Y family, which includes several GPCRs that are P2Y(cyc) is widely expressed in various tissues and has been implicated in various physiological processes, including pain perception, neurotransmission, and neuroprotection.
Drugs that target P2Y(cyc) have the potential to treat various neurological and psychiatric disorders, including pain, anxiety, and depression. Therefore, the development of small molecules that specifically target P2Y(cyc) has become an attractive research topic in the pharmaceutical industry . In this article, we will discuss the biology of P2Y(cyc), its role in pain modulation, and the potential drug targets associated with P2Y(cyc).
biological background
P2Y (cyc) is a G protein-coupled receptor (GPCR) that plays an important role in pain modulation, neurotransmitter signaling, and neurotransmitter transmission. It is a member of the P2Y family, which also includes other GPCRs involved in various physiological processes, including cardiovascular, pain, and neurotransmission. P2Y(cyc) is widely expressed in various tissues and is closely related to pain sensation, neurotransmission and neuroprotection.
medical treatement
Research on targeted therapeutic drugs for P2Y(cyc) is an important area of 鈥嬧?媙euroscience and pharmacology research. Many P2Y (
Protein Name: Purinergic Receptor P2Y12
Functions: Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation
More Common Targets
P2RY13 | P2RY14 | P2RY2 | P2RY4 | P2RY6 | P2RY8 | P2X Receptor | P2Y purinoceptor | P3H1 | P3H2 | P3H3 | P3H4 | P3R3URF-PIK3R3 | P4HA1 | P4HA2 | P4HA3 | P4HB | P4HTM | PA28 Complex | PA28gamma Complex | PA2G4 | PA2G4P1 | PA2G4P4 | PAAF1 | PABIR1 | PABIR2 | PABIR3 | PABP-dependent poly(A) nuclease (PAN) complex | PABPC1 | PABPC1L | PABPC1L2A | PABPC1L2B | PABPC1P10 | PABPC1P2 | PABPC1P4 | PABPC1P7 | PABPC3 | PABPC4 | PABPC4-AS1 | PABPC4L | PABPC5 | PABPN1 | PABPN1L | PACC1 | PACERR | PACRG | PACRG-AS2 | PACRGL | PACS1 | PACS2 | PACSIN1 | PACSIN2 | PACSIN3 | PADI1 | PADI2 | PADI3 | PADI4 | PADI6 | PAEP | PAEPP1 | PAF1 | PAF1 complex | PAFAH1B1 | PAFAH1B2 | PAFAH1B2P2 | PAFAH1B3 | PAFAH2 | PAG1 | PAGE1 | PAGE2 | PAGE2B | PAGE3 | PAGE4 | PAGE5 | PAGR1 | PAH | PAICS | PAICSP4 | PAIP1 | PAIP1P1 | PAIP2 | PAIP2B | PAK1 | PAK1IP1 | PAK2 | PAK3 | PAK4 | PAK5 | PAK6 | PAK6-AS1 | PALB2 | PALD1 | PALLD | PALM | PALM2 | PALM2AKAP2 | PALM3 | PALMD | Palmitoyltransferase | PALS1