Pak6-AS1: A Potential Drug Target Or Biomarker (G644809)

Target Name: PAK6-AS1

NCBI ID: G644809

Pak6-AS1: A Potential Drug Target Or Biomarker

Pak6-AS1, also known as PAK6-AS1, is a protein that is expressed in various tissues, including the brain, heart, and kidneys, and is involved in the regulation of cell signaling pathways. It is a putative uncharacterized protein that has been identified using various bioinformatics and biochemical approaches. This protein has been shown to play a significant role in several biological processes, including cell adhesion, migration, and invasion, and is thus a potential drug target or biomarker.

Pak6-AS1: Structure and Function

The protein Pak6-AS1 is a member of the tyrosine kinase family and has a molecular weight of approximately 110 kDa. It consists of a 215 amino acid residue protein that contains several unique features, including a long N-terminus, a single transmembrane segment, and a complex cytoplasmic region.

The N-terminus of Pak6-AS1 contains a unique feature that is composed of a variable region and a constant region. The variable region includes several conserved domains, including a putative N-endonuclease domain, a potential tyrosine kinase domain, and a variable region that contains several un conserved amino acids. The constant region includes a unique domain that is involved in the regulation of cell signaling pathways, including the GTPase-activating protein (GAP) signaling pathway.

The cytoplasmic region of Pak6-AS1 is characterized by the presence of several unique features, including a long terminal region that is involved in the regulation of cell adhesion and migration, and a region that is involved in the regulation of cell invasion and metastasis.

Pak6-AS1: Putative Functions

Pak6-AS1 has been shown to play a significant role in several biological processes, including cell adhesion, migration, and invasion.

First, Pak6-AS1 is involved in the regulation of cell adhesion. It has been shown to play a role in the regulation of tight junction formation and cell-cell adhesion, and to interact with several cytoskeleton proteins, including tubulin (MAPK/ ERK) and spinal gray matter glial-axonal glial synapses (GBP). Through these interactions, Pak6-AS1 can regulate cell membrane tension and influence cell behavior, including endocytosis and cell adhesion.

Second, Pak6-AS1 is involved in cell migration and invasion. It has been shown to play a role in the regulation of cell migration and the invasive properties of cancer cells, by regulating the activity of several cytoskeleton proteins, including tubulin (MAPK) /ERK) and histones (H3K9me3). Through these interactions, Pak6-AS1 can regulate the remodeling of the cytoskeleton, affecting cell migration and aggressive behavior.

Third, Pak6-AS1 is involved in the regulation of cell signaling pathways. It has been shown to play a role in the regulation of several signaling pathways, including the GTPase-activating protein (GAP) signaling pathway. Through these interactions, Pak6- AS1 can regulate the concentration and balance of intracellular signaling molecules and affect cell behavior, including cell proliferation, apoptosis, etc.

Conclusion

Pak6-AS1 is a putative uncharacterized protein that has been identified using various bioinformatics and biochemical approaches. It is a member of the tyrosine kinase family and has several unique features, including a long N-terminus, a single transmembrane segment, and a complex cytoplasmic region. Pak6-AS1 has been shown to play a significant role in several biological processes, including cell adhesion, migration, and invasion, and is thus a potential drug target or biomarker. Further studies are needed to fully understand the functions of Pak6-AS1 and its potential as a drug.

Protein Name: PAK6 Antisense RNA 1

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