Palm3: A Potential Drug Target and Biomarker for Various Diseases

Target Name: PALM3

NCBI ID: G342979

Palm3: A Potential Drug Target and Biomarker for Various Diseases

Palm3 (PALM3_HUMAN) is a protein that is expressed in human tissues and is known for its role in cell signaling. It is a potential drug target and has been identified as a biomarker for various diseases, including cancer.

Palm3 is a member of the PALM gene family, which is known for its role in cell signaling. PALM3 and its associated proteins are involved in the regulation of various cellular processes, including cell adhesion, migration, and invasion.

One of the unique aspects of Palm3 is its expression in human tissues. While it is not typically expressed in human placenta, it is expressed in various other tissues, including the brain, heart, and muscle. This makes it a potential drug target that can be targeted without ethical concerns associated with targeting human placenta.

Palm3 has also been identified as a potential biomarker for various diseases, including cancer. Its expression has been observed in various types of cancer, including breast, lung, and ovarian cancer. This suggests that Palm3 may be a useful marker for the diagnosis and prognosis of cancer.

In addition to its potential drug target and biomarker properties, Palm3 is also of interest due to its structure and function. The PALM3 protein is composed of 21kDa, and consists of a 16kDa transmembrane region and a 5kDa cytoplasmic tail. It has a highly conserved cytoplasmic region, which is indicative of its role in intracellular signaling.

Palm3 is involved in various signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key target for many diseases, including cancer.

In conclusion, Palm3 is a protein that is of interest due to its potential drug target and biomarker properties. Its high conservation cytoplasmic region and its involvement in various signaling pathways make it a promising target for drug development. Further research is needed to fully understand its role in cell signaling and its potential as a drug or biomarker.

Protein Name: Paralemmin 3

Functions: ATP-binding protein, which may act as a adapter in the Toll-like receptor (TLR) signaling

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