PARD6G: A Potential Drug Target and Biomarker (G84552)

Target Name: PARD6G

NCBI ID: G84552

PARD6G: A Potential Drug Target and Biomarker

Pard6g, also known as FLJ45701, is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. Its function is not well understood, but it is known to play a role in the regulation of cell proliferation and survival. Several studies have suggested that Pard6g may have potential as a drug target or biomarker.

The protein Pard6g is a member of the Pard family of proteins, which are known to play a role in the regulation of cell growth and differentiation. Pard6g is similar to other proteins in the Pard family, such as Pardin and Pardroptidin, which are also known to be involved in the regulation of cell proliferation and survival.

One of the key functions of Pard6g is its role in the regulation of cell proliferation. Several studies have shown that Pard6g plays a negative role in the regulation of cell proliferation by inhibiting the activity of the oncogene transforming growth factor beta (TGF-β). TGF-β is a well-known protein that is involved in the regulation of cell growth, including cell proliferation.

In addition to its role in cell proliferation, Pard6g has also been shown to play a role in the regulation of cell survival. Several studies have shown that Pard6g plays a negative role in the regulation of cell survival by inhibiting the activity of the neurotrophic factor PDGF. PDGF is a protein that is involved in the regulation of cell survival, including the survival of brain cells.

The potential drug target status of Pard6g is further supported by its expression in various tissues of the human body, including the brain. The brain is a particularly sensitive to changes in cell proliferation and survival, making it an attractive target for drugs that are designed to inhibit the activity of Pard6g.

In conclusion, Pard6g is a protein that is known to play a role in the regulation of cell proliferation and survival. Its potential as a drug target or biomarker makes it an attractive target for future studies. Further research is needed to fully understand the function of Pard6g and its potential as a drug.

Protein Name: Par-6 Family Cell Polarity Regulator Gamma

Functions: Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity)

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