Target Name: OR8B4
NCBI ID: G283162
Other Name(s): olfactory receptor family 8 subfamily B member 4 | Olfactory receptor family 8 subfamily B member 4 | olfactory receptor, family 8, subfamily B, member 4 pseudogene | OR11-315 | OR8B4_HUMAN | OR8B4P | Olfactory receptor 8B4 | olfactory receptor OR11-315 | Olfactory receptor OR11-315 | Olfactory receptor, family 8, subfamily B, member 4 pseudogene

OR8B4 as A Drug Target Or Biomarker for Cancer and Neurodegenerative Diseases

OR8B4 (Olfactory Receptor Family 8 Subfamily B Member 4) is a protein that is expressed in the olfactory epithelium, which is the lining of the nose. OR8B4 is a member of the olfactory receptor family 8, which is responsible for transmitting odor information from the nose to the brain. OR8B4 is a potential drug target or biomarker for several reasons.

One reason why OR8B4 could be a drug target is because it is involved in the sense of smell. OR8B4 is responsible for detecting the chemical components of odors, which are then sent to the brain via the olfactory nerve. Studies have shown that people with conditions such as Alzheimer's disease and Parkinson's disease have reduced levels of OR8B4 in their brains. This suggests that targeting OR8B4 could be a way to treat these conditions. Additionally, high levels of OR8B4 have been associated with certain cancers, so targeting this protein could also be a way to treat cancer.

Another reason why OR8B4 could be a drug target is because it is involved in the development and progression of several diseases. For example, OR8B4 has been shown to be involved in the development of cancer, including breast and ovarian cancer. Additionally, OR8B4 has been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. This suggests that targeting OR8B4 could be a way to treat these conditions.

OR8B4 is also a potential biomarker for several diseases. For example, high levels of OR8B4 have been shown to be associated with the development of certain cancers, including breast and ovarian cancer. Additionally, OR8B4 has been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. This suggests that targeting OR8B4 could be a way to diagnose and monitor these conditions.

Targeting OR8B4 could also be a way to treat other conditions that are related to the sense of smell. For example, some people with smell loss due to cancer treatment may benefit from drugs that target OR8B4. Additionally, people with unexplained smell loss may benefit from drugs that target OR8B4.

In conclusion, OR8B4 is a protein that is expressed in the olfactory epithelium and is involved in the sense of smell. OR8B4 is also a potential drug target or biomarker for several diseases, including cancer and neurodegenerative conditions. Further research is needed to understand the role of OR8B4 in these conditions and to develop effective treatments.

Protein Name: Olfactory Receptor Family 8 Subfamily B Member 4

Functions: Odorant receptor

More Common Targets

OR8B6P | OR8B7P | OR8B8 | OR8D1 | OR8D2 | OR8D4 | OR8F1P | OR8G1 | OR8G2P | OR8G3P | OR8G5 | OR8G7P | OR8H1 | OR8H2 | OR8H3 | OR8I2 | OR8J1 | OR8J3 | OR8K1 | OR8K3 | OR8K5 | OR8S1 | OR8U1 | OR8U3 | OR8U8 | OR9A1P | OR9A2 | OR9A4 | OR9G1 | OR9G4 | OR9G9 | OR9H1P | OR9I1 | OR9K2 | OR9Q1 | OR9Q2 | ORAI1 | ORAI2 | ORAI3 | ORC1 | ORC2 | ORC3 | ORC4 | ORC5 | ORC6 | Orexin receptor | Organic anion transporters (OATs) | Organic cation transporter | Origin recognition complex | ORM1 | ORM2 | ORMDL1 | ORMDL2 | ORMDL3 | OS9 | OSBP | OSBP2 | OSBPL10 | OSBPL11 | OSBPL1A | OSBPL2 | OSBPL3 | OSBPL5 | OSBPL6 | OSBPL7 | OSBPL8 | OSBPL9 | OSCAR | OSCP1 | OSER1 | OSER1-DT | OSGEP | OSGEPL1 | OSGEPL1-AS1 | OSGIN1 | OSGIN2 | OSM | OSMR | OSMR-DT | OSR1 | OSR2 | OST4 | OSTC | OSTCP1 | OSTF1 | OSTF1P1 | OSTM1 | OSTM1-AS1 | OSTN | OSTN-AS1 | OTC | OTOA | OTOAP1 | OTOF | OTOG | OTOGL | OTOL1 | OTOP1 | OTOP2 | OTOP3