Target Name: MRPS28
NCBI ID: G28957
Other Name(s): MRP-S28 | MRPS35 | RT28_HUMAN | S35mt | S28mt | 28S ribosomal protein S35, mitochondrial | mitochondrial ribosomal protein S28 | COXPD47 | mitochondrial 28S ribosomal protein S35 | Mitochondrial small ribosomal subunit protein bS1m | HSPC007 | 28S ribosomal protein S28, mitochondrial | MRP-S35 | Mitochondrial ribosomal protein S28 | mitochondrial small ribosomal subunit protein bS1m

MRPS28: A Potential Drug Target and Biomarker

MRP (MutL-RISC-Box) is a protein that plays a crucial role in the regulation of gene expression in bacteria. It is a transmembrane protein that contains a nucleotide-binding oligomerization domain (NBD) and a RING-like domain. MRP has has been identified as a potential drug target in the field of cancer and neurodegenerative diseases due to its involvement in the regulation of cellular processes that are important for disease progression.

The MRP gene was identified in the GenBank database and has been annotated as a gene that is involved in the regulation of gene expression in Pseudomonas aeruginosa, a bacterium that is commonly found in water treatment systems and can cause a range of diseases, including cancer, pneumonia, and meningitis. The gene is located on chromosome 1 and has 28 exons.

The NBD and RING-like domains of MRP are responsible for its unique structure and function. The NBD is a transmembrane domain that contains a nucleotide-binding oligomerization domain (NBD) and a farnesylated cysteine 鈥嬧?媟esidue. The NBD plays a critical role in the regulation of gene expression by binding to specific DNA sequences. The RING-like domain is a short, conserved protein domain that is located between the NBD and the RING-like domain. It is responsible for the interaction between the NBD and the DNA.

The MRP protein has been shown to play a role in the regulation of cellular processes that are important for disease progression. For example, MRP has been shown to be involved in the regulation of cell cycle progression in Pseudomonas aeruginosa. MRP has been shown to inhibit the G1 phase of the cell cycle, which is the phase of growth and division, and this inhibition leads to the arrest of cell division. This is important for the regulation of cellular processes that are important for disease progression, such as cancer development.

In addition to its role in cell cycle regulation, MRP has also been shown to be involved in the regulation of gene expression. For example, MRP has been shown to play a role in the regulation of the expression of the bacterial efflux pumps, which are proteins that are responsible for pumping antibiotics out of bacterial cells. The efflux pumps are important for the defense of bacteria against antibiotics, and their regulation by MRP is important for the survival of Pseudomonas aeruginosa.

The potential drug target status of MRP is due to its involvement in the regulation of cellular processes that are important for disease progression. Cancer is a disease that is characterized by the uncontrolled growth and division of cells, and it is a leading cause of death in the world. The regulation of cellular processes that are important for cancer development and progression is a critical aspect of understanding the disease and developing effective treatments. MRP has been shown to play a role in this regulation, and as a potential drug target, it is a promising target for cancer and neurodegenerative diseases.

In conclusion, MRP is a protein that has been identified as a potential drug target due to its involvement in the regulation of cellular processes that are important for disease progression. The NBD and RING-like domains of MRP have been shown to play critical roles in its function, and its regulation of gene expression is an important aspect of its potential drug target status. Further research is needed to fully understand the function of MRP and its potential as a drug target.

Protein Name: Mitochondrial Ribosomal Protein S28

More Common Targets

MRPS30 | MRPS30-DT | MRPS31 | MRPS31P2 | MRPS31P4 | MRPS31P5 | MRPS33 | MRPS33P4 | MRPS34 | MRPS35 | MRPS35-DT | MRPS36 | MRPS36P4 | MRPS5 | MRPS6 | MRPS7 | MRPS9 | MRRF | MRS2 | MRS2P2 | MRTFA | MRTFB | MRTO4 | MS4A1 | MS4A10 | MS4A12 | MS4A13 | MS4A14 | MS4A15 | MS4A18 | MS4A2 | MS4A3 | MS4A4A | MS4A4E | MS4A5 | MS4A6A | MS4A6E | MS4A7 | MS4A8 | MSANTD1 | MSANTD2 | MSANTD3 | MSANTD4 | MSC | MSC-AS1 | MSGN1 | MSH2 | MSH3 | MSH4 | MSH5 | MSH5-SAPCD1 | MSH6 | MSI1 | MSI2 | MSL1 | MSL2 | MSL3 | MSL3P1 | MSLN | MSLNL | MSMB | MSMO1 | MSMP | MSN | MSNP1 | MSR1 | MSRA | MSRA-DT | MSRB1 | MSRB1P1 | MSRB2 | MSRB3 | MSRB3-AS1 | MSS51 | MST1 | MST1L | MST1P2 | MST1R | MSTN | MSTO1 | MSTO2P | MSX1 | MSX2 | MSX2P1 | MT1A | MT1B | MT1DP | MT1E | MT1F | MT1G | MT1H | MT1HL1 | MT1IP | MT1JP | MT1L | MT1M | MT1P1 | MT1P3 | MT1X | MT1XP1