Target Name: MRS2
NCBI ID: G57380
Other Name(s): MRS2_HUMAN | MRS2-like protein | HPT | MRS2L | putative magnesium transporter | MGC78523 | Magnesium transporter MRS2 homolog, mitochondrial | MRS2 variant 2 | MRS2, magnesium transporter | Magnesium transporter MRS2 homolog, mitochondrial (isoform b) | Magnesium transporter MRS2, transcript variant 2 | MRS2-like, magnesium homeostasis factor | magnesium transporter MRS2

MRS2: A Potential Drug Target Or Biomarker

MRS2 (MRS2_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, spleen, and pancreas. It is a member of the MRS2 gene family, which encodes for a protein that is involved in the development and maintenance of tissues, as well as the regulation of cellular processes.

MRS2 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these processes has led to it being considered as a potential drug target or biomarker.

One of the key functions of MRS2 is its role in the regulation of stem cell proliferation. MRS2 has been shown to play a role in the control of stem cell self-renewal and differentiation, as well as the regulation of stem cell plasticity.

MRS2 has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cell function and the production of inflammatory cytokines.

In addition to its role in the regulation of stem cells and inflammation, MRS2 has also been shown to be involved in the regulation of cellular processes that are important for maintaining tissue homeostasis. This includes the regulation of cell migration, the formation of blood vessels, and the regulation of ion homeostasis.

MRS2 has also been shown to be involved in the development and progression of various diseases, including cancer. For example, studies have shown that MRS2 is often overexpressed in various types of cancer, and that inhibition of MRS2 has been shown to be effective in treating these diseases.

In addition to its potential as a drug target or biomarker, MRS2 has also been shown to be a useful diagnostic tool. Studies have shown that MRS2 is expressed in various tissues of the human body, including the brain, spleen, and pancreas, and that it is often overexpressed in various types of cancer. This makes it a potential diagnostic tool for diseases that are characterized by the over-expression of MRS2.

Overall, MRS2 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role in these processes and to develop effective treatments for MRS2-related diseases.

Protein Name: Magnesium Transporter MRS2

Functions: Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix (PubMed:11401429, PubMed:18384665). Required for normal expression of the mitochondrial respiratory complex I subunits (PubMed:18384665)

More Common Targets

MRS2P2 | MRTFA | MRTFB | MRTO4 | MS4A1 | MS4A10 | MS4A12 | MS4A13 | MS4A14 | MS4A15 | MS4A18 | MS4A2 | MS4A3 | MS4A4A | MS4A4E | MS4A5 | MS4A6A | MS4A6E | MS4A7 | MS4A8 | MSANTD1 | MSANTD2 | MSANTD3 | MSANTD4 | MSC | MSC-AS1 | MSGN1 | MSH2 | MSH3 | MSH4 | MSH5 | MSH5-SAPCD1 | MSH6 | MSI1 | MSI2 | MSL1 | MSL2 | MSL3 | MSL3P1 | MSLN | MSLNL | MSMB | MSMO1 | MSMP | MSN | MSNP1 | MSR1 | MSRA | MSRA-DT | MSRB1 | MSRB1P1 | MSRB2 | MSRB3 | MSRB3-AS1 | MSS51 | MST1 | MST1L | MST1P2 | MST1R | MSTN | MSTO1 | MSTO2P | MSX1 | MSX2 | MSX2P1 | MT1A | MT1B | MT1DP | MT1E | MT1F | MT1G | MT1H | MT1HL1 | MT1IP | MT1JP | MT1L | MT1M | MT1P1 | MT1P3 | MT1X | MT1XP1 | MT2A | MT3 | MT4 | MTA1 | MTA1-DT | MTA2 | MTA3 | MTAP | MTARC1 | MTARC2 | MTATP6P1 | MTATP8P1 | MTBP | MTCH1 | MTCH2 | MTCL1 | MTCO1P1 | MTCO1P12 | MTCO1P15