Target Name: MTBP
NCBI ID: G27085
Other Name(s): MDM2 (mouse double minute 2)-binding protein, 104kD | Mdm2-binding protein | MDM2BP | MTBP_HUMAN | MDM2 binding protein | hMTBP | Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa

MTBP: A Potential Drug Target Or Biomarker

Mouse Double Minute 2 (MTBP) is a protein that is expressed in the liver and other tissues of mice. It is a member of the evolutionarily conserved superfamily of proteins that includes several other well-studied proteins, including the protein encoded by the human gene CD28.

MTBP is highly conserved, with a calculated molecular weight of 104 kDa. It is found in various tissues and organs, including the liver, spleen, heart, and lymphoid organs. MTBP is also expressed in human tissues, and has been used as a potential drug target or biomarker in several studies.

One of the key functions of MTBP is its role in the immune response. MTBP is a known receptor for the T cell receptor, which is a critical molecule that recognizes foreign antigens and activates an immune response. MTBP has been shown to play a role in regulating the activity of T cells, and has been shown to interact with several other proteins involved in the immune response.

In addition to its role in the immune response, MTBP has also been shown to have several other functions that are relevant to its potential as a drug target or biomarker. For example, MTBP has been shown to play a role in the regulation of cell growth and differentiation, and has been shown to interact with several proteins involved in these processes. MTBP has also been shown to play a role in the regulation of cell survival and apoptosis, and has been shown to interact with several proteins involved in these processes.

Despite its potential as a drug target or biomarker, little is currently known about the specific mechanisms by which MTBP functions. However, several studies have shown that MTBP interacts with several proteins involved in the immune response, and that these interactions may be important for its functions.

In conclusion, MTBP is a protein that has been shown to play a role in several important functions, including the regulation of the immune response and the regulation of cell growth and apoptosis. As a potential drug target or biomarker, MTBP is a promising target for future research. Further studies are needed to fully understand its mechanisms of action and to determine its potential as a therapeutic agent.

Protein Name: MDM2 Binding Protein

Functions: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation

More Common Targets

MTCH1 | MTCH2 | MTCL1 | MTCO1P1 | MTCO1P12 | MTCO1P15 | MTCO2P33 | MTCO3P1 | MTCO3P12 | MTCP1 | MTDH | MTERF1 | MTERF2 | MTERF3 | MTERF4 | MTF1 | MTF2 | MTFMT | MTFP1 | MTFR1 | MTFR1L | MTFR2 | MTG1 | MTG2 | MTHFD1 | MTHFD1L | MTHFD2 | MTHFD2L | MTHFD2P7 | MTHFR | MTHFS | MTHFSD | MTIF2 | MTIF3 | MTLN | MTM1 | MTMR1 | MTMR10 | MTMR11 | MTMR12 | MTMR14 | MTMR2 | MTMR3 | MTMR4 | MTMR6 | MTMR7 | MTMR8 | MTMR9 | MTMR9LP | MTND1P11 | MTND1P23 | MTND1P3 | MTND1P33 | MTND2P21 | MTND2P28 | MTND4P10 | MTND4P12 | MTND4P17 | MTND4P22 | MTND4P24 | MTND4P28 | MTND4P29 | MTND5P10 | MTND5P16 | MTND5P19 | MTND5P20 | MTND5P31 | MTND5P8 | MTND6P14 | MTND6P4 | MTNR1A | MTNR1B | MTO1 | MTOR | mTOR complex 1 | mTOR complex 2 | MTPAP | MTPN | MTR | MTRES1 | MTREX | MTRF1 | MTRF1L | MTRF1LP2 | MTRFR | MTRNR2L1 | MTRNR2L10 | MTRNR2L11 | MTRNR2L12 | MTRNR2L13 | MTRNR2L2 | MTRNR2L3 | MTRNR2L4 | MTRNR2L5 | MTRNR2L6 | MTRNR2L7 | MTRNR2L8 | MTRNR2L9 | MTRR | MTSS1