Target Name: MTMR12
NCBI ID: G54545
Other Name(s): Myotubularin related protein 12, transcript variant 1 | PIP3AP | Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit | Myotubularin-related protein 12 (isoform 1) | inactive phosphatidylinositol 3-phosphatase 12 | Myotubularin-related protein 12 | 3-PAP | MTMR12 variant 1 | Inactive phosphatidylinositol 3-phosphatase 12 | Phosphatidylinositol-3 phosphate 3-phosphatase adaptor subunit | Phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit | 3-phosphatase adapter subunit | Phosphatidylinositol-3-phosphate associated protein | myotubularin related protein 12 | phosphatidylinositol-3 phosphate 3-phosphatase adaptor subunit | phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit | 3-phosphatase adapter protein | phosphatidylinositol-3-phosphate associated protein | MTMRC_HUMAN

MTMR12: A Drug Target / Disease Biomarker

MTMR12 is a drug target and a potential biomarker for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function make it an attractive target for drug development.

MTMR12 is a protein that is expressed in various tissues and cells of the body. Its name comes from its structure, which is similar to that of the disease melanoma, a type of skin cancer. The protein is composed of four subunits that are held together by non-covalent bonds. These subunits give MTMR12 its unique structure and stability, allowing it to function in a variety of settings.

One of the most significant features of MTMR12 is its role in the development and progression of cancer. Studies have shown that MTMR12 is highly expressed in various types of cancer, including breast, ovarian, and prostate cancer. It has also been shown to be involved in the regulation of cell growth and survival, which are key factors in the development of cancer.

In addition to its role in cancer, MTMR12 has also been shown to be involved in the development and progression of neurodegenerative diseases. These diseases include Alzheimer's disease, Parkinson's disease, and Huntington's disease, among others. Studies have shown that MTMR12 is involved in the regulation of neurotransmitter signaling, which is crucial for the function of nerve cells.

Another potential application of MTMR12 as a drug target is its role in the treatment of autoimmune disorders. These disorders affect the immune system and can cause a wide range of symptoms, including inflammation, pain, and fatigue. MTMR12 has been shown to be involved in the regulation of immune cell function, which may make it an attractive target for the development of new treatments for autoimmune disorders.

In conclusion, MTMR12 is a drug target and a potential biomarker that has the potential to revolutionize the treatment of a wide range of diseases. Its unique structure and function make it an attractive target for drug development, and its involvement in the development and progression of cancer and neurodegenerative diseases makes it an important area of research. Further studies are needed to fully understand the potential of MTMR12 as a drug and biomarker.

Protein Name: Myotubularin Related Protein 12

Functions: Acts as an adapter for the myotubularin-related phosphatases (PubMed:11504939, PubMed:12847286, PubMed:23818870). Regulates phosphatase MTM1 protein stability and possibly its intracellular location (PubMed:23818870). By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity)

More Common Targets

MTMR14 | MTMR2 | MTMR3 | MTMR4 | MTMR6 | MTMR7 | MTMR8 | MTMR9 | MTMR9LP | MTND1P11 | MTND1P23 | MTND1P3 | MTND1P33 | MTND2P21 | MTND2P28 | MTND4P10 | MTND4P12 | MTND4P17 | MTND4P22 | MTND4P24 | MTND4P28 | MTND4P29 | MTND5P10 | MTND5P16 | MTND5P19 | MTND5P20 | MTND5P31 | MTND5P8 | MTND6P14 | MTND6P4 | MTNR1A | MTNR1B | MTO1 | MTOR | mTOR complex 1 | mTOR complex 2 | MTPAP | MTPN | MTR | MTRES1 | MTREX | MTRF1 | MTRF1L | MTRF1LP2 | MTRFR | MTRNR2L1 | MTRNR2L10 | MTRNR2L11 | MTRNR2L12 | MTRNR2L13 | MTRNR2L2 | MTRNR2L3 | MTRNR2L4 | MTRNR2L5 | MTRNR2L6 | MTRNR2L7 | MTRNR2L8 | MTRNR2L9 | MTRR | MTSS1 | MTSS2 | MTTP | MTURN | MTUS1 | MTUS1-DT | MTUS2 | MTUS2-AS1 | MTVR2 | MTX1 | MTX2 | MTX3 | mu-Calpain (calpain 1) | MUC1 | MUC12 | MUC13 | MUC15 | MUC16 | MUC17 | MUC19 | MUC2 | MUC20 | MUC20P1 | MUC21 | MUC22 | MUC3A | MUC3B | MUC4 | MUC5AC | MUC5B | MUC6 | MUC7 | MUC8 | Mucin | MUCL1 | MUCL3 | MUL1 | Multisubunit histone acetyltransferase complex | MUPP | MUS81 | Muscarinic Acetylcholine Receptor (mAChR)