Target Name: MTURN
NCBI ID: G222166
Other Name(s): maturin, neural progenitor differentiation regulator homolog | MTURN_HUMAN | Maturin, neural progenitor differentiation regulator homolog | Protein Ells1 | Ells1 | Maturin | Maturin neural progenitor differentiation regulator protein homolog | C7orf41 | protein Ells1 | maturin neural progenitor differentiation regulator protein homolog | UPF0452 protein C7orf41

MTURN: A Protein Involved in Neuron Development and Growth

MTURN, or Maturin, is a protein that is expressed in the neural progenitor cells of the brain. It is a neural progenitor differentiation regulator homolog and is involved in the process of neuron development and growth.

MTURN has been shown to play a role in the development and progression of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and neurodegenerative diseases. It has also been linked to the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time.

One of the key functions of MTURN is its role in the regulation of neuron stem cells. These cells are responsible for the development and maintenance of the nervous system, and are a crucial part of the repair process after a neurodegenerative disorder. MTURN has been shown to help control the number of neuron stem cells and to regulate their proliferation.

In addition to its role in neuron stem cells, MTURN is also involved in the regulation of neuron survival. Studies have shown that MTURN plays a role in the regulation of cell survival and that its expression is often reduced in neurodegenerative disorders. This may be because of its role in the regulation of cell cycle progression, which is the process by which cells divide and grow.

MTURN has also been shown to be involved in the regulation of neural plasticity, which is the ability of the brain to change and adapt over time. This is important for the development and progression of various neurological disorders, as well as for maintaining the proper functioning of the nervous system.

In conclusion, MTURN is a protein that is expressed in the neural progenitor cells of the brain and is involved in the process of neuron development and growth. Its role in the regulation of neuron stem cells, cell survival, and neural plasticity makes it a potential drug target and a biomarker for various neurological disorders. Further research is needed to fully understand the role of MTURN in neurological disease and to develop effective treatments.

Protein Name: Maturin, Neural Progenitor Differentiation Regulator Homolog

Functions: Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (PubMed:24681962). Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser-536' (PubMed:24681962). May be involved in early neuronal development (By similarity)

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