MT1B: A Protein Regulating T Cells, Inflammation and Cell Death

Target Name: MT1B

NCBI ID: G4490

MT1B: A Protein Regulating T Cells, Inflammation and Cell Death

MT1B, also known as metallothionein 1B, is a protein that is expressed in a variety of tissues throughout the body. It is a key regulator of the immune response and has been shown to play a role in a number of diseases, including cancer, autoimmune disorders, and chronic obstructive pulmonary disease (COPD). In recent years, researchers have been investigating the potential uses of MT1B as a drug target or biomarker, and new studies are providing promising results.

MT1B is a member of the thymus family, which includes proteins that are involved in the development and maintenance of the thymus gland. The thymus is a vital organ that plays a critical role in the immune system, producing T cells, which are responsible for fighting off infections and cancer. MT1B is expressed in the thymus, and it has been shown to play a key role in the regulation of T cell development and function.

One of the key functions of MT1B is its role as a regulator of the immune response. MT1B has been shown to help control the production of T cells by suppressing the activity of a protein called T-cell factor (TGF-1). TGF-1 is a critical regulator of T cell development, and it has been shown to play a role in a number of diseases, including cancer. By suppressing TGF-1 activity, MT1B may help to prevent the development of T cells that could contribute to the development of cancer.

In addition to its role in T cell regulation, MT1B has also been shown to play a role in the regulation of inflammation. MT1B has been shown to help control the production of pro-inflammatory molecules, such as cytokines and chemokines, which can contribute to the development of inflammatory diseases. By regulating the production of these molecules, MT1B may help to prevent the development of inflammatory diseases and reduce their severity.

MT1B has also been shown to play a role in the regulation of cell death, which is an important part of the immune response. MT1B has been shown to help control the production of proteins that promote cell death, which may help to prevent the development of cancer.

In conclusion, MT1B is a protein that is expressed in a variety of tissues throughout the body and has been shown to play a role in a number of diseases, including cancer, autoimmune disorders, and COPD. MT1B's role in T cell regulation, inflammation, and cell death makes it an attractive target for research into new treatments. Further studies are needed to fully understand the potential uses of MT1B as a drug or biomarker.

Protein Name: Metallothionein 1B

Functions: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids

More Common Targets