Target Name: BEND4
NCBI ID: G389206
Other Name(s): BEND4 variant 1 | CCDC4 | BEND4_HUMAN | BEN domain containing 4 | coiled-coil domain-containing protein 4 | BEN domain containing 4, transcript variant 2 | BEN domain-containing protein 4 (isoform a) | coiled-coil domain containing 4 | BEN domain containing 4, transcript variant 1 | FLJ43965 | BEN domain-containing protein 4 (isoform b) | BEND4 variant 2 | BEN domain-containing protein 4 | Coiled-coil domain-containing protein 4 | Hypothetical protein LOC389206 | FLJ35632

BEND4: The Potential Drug Target and Biomarker

BEND4, also known as BEND4 variant 1, is a gene that encodes a protein involved in the regulation of cell growth and differentiation. The study of BEND4 and its associated proteins has gained significant attention in recent years due to its potential involvement in various diseases, including cancer. In this article, we will explore the potential drug target and biomarker properties of BEND4.

The Role of BEND4 in Cellular Regulation

BEND4 is a key regulator of cell growth and differentiation, playing a critical role in the development and maintenance of tissues and organs. It is expressed in various tissues, including muscle, heart, brain, and organs, and has been implicated in the regulation of stem cell proliferation, differentiation, and plasticity.

One of the key functions of BEND4 is its role in the regulation of cell proliferation. BEND4 has been shown to inhibit the growth of cancer cells and to promote the growth of healthy tissues. This is achieved by regulating the activity of several cellular signaling pathways, including the TGF-β pathway, which plays a major role in cancer cell growth and proliferation.

Another function of BEND4 is its role in the regulation of cell differentiation. BEND4 has been shown to promote the development of specific cell types, such as neurons and muscle cells, and to regulate their subsequent plasticity. This is achieved by regulating the activity of several signaling pathways, including the Wnt pathway, which plays a critical role in the development and maintenance of neural tissue.

The Potential Role of BEND4 as a Drug Target

The potential drug target properties of BEND4 are due to its involvement in various cellular processes that are important for human health and disease. One of the key benefits of targeting BEND4 is its potential to treat various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

In cancer, BEND4 has been shown to be involved in the regulation of cell proliferation and has been implicated in the development and progression of various types of cancer. For example, studies have shown that BEND4 is involved in the regulation of the growth and survival of breast cancer cells and that inhibition of its activity may be a promising therapeutic approach for breast cancer treatment.

In neurodegenerative diseases, BEND4 has been shown to be involved in the regulation of neural tissue development and plasticity. For example, studies have shown that BEND4 is involved in the regulation of the growth and differentiation of neural stem cells and that disruption of its activity may contribute to the development of neurodegenerative diseases.

In developmental disorders, BEND4 has been shown to be involved in the regulation of cell proliferation and development. For example, studies have shown that BEND4 is involved in the regulation of the growth and development of neural tissue in the developing brain and that disruption of its activity may contribute to the development of developmental disorders.

The Potential Role of BEND4 as a Biomarker

The potential use of BEND4 as a biomarker for various diseases is based on its involvement in several cellular processes that are important for human health and disease. One of the key benefits of using BEND4 as a biomarker is its potential to provide sensitive and specific detection of disease markers, which can be used to diagnose and monitor disease progression.

In cancer, BEND4 has been shown to be involved in the regulation of cell proliferation and has been implicated in the development and progression of various types of cancer. Therefore, its expression level may be an useful biomarker for cancer diagnosis and monitoring.

In neurodegenerative diseases, BEND4 has been shown to be involved in the regulation of neural tissue development and plasticity. Therefore, its expression level may be an useful biomarker for neurodegenerative diseases

Protein Name: BEN Domain Containing 4

More Common Targets

BEND5 | BEND6 | BEND7 | BEST1 | BEST2 | BEST3 | BEST4 | BET1 | BET1L | beta-Adrenoceptor | beta-Crystallin | beta-Hexosaminidase Complex | beta-Secretase | BEX1 | BEX2 | BEX3 | BEX4 | BEX5 | BFAR | BFSP1 | BFSP2 | BFSP2-AS1 | BGLAP | BGLT3 | BGN | BHC complex | BHLHA15 | BHLHA9 | BHLHE22 | BHLHE22-AS1 | BHLHE23 | BHLHE40 | BHLHE40-AS1 | BHLHE41 | BHMT | BHMT2 | BICC1 | BICD1 | BICD2 | BICDL1 | BICDL2 | BICRA | BICRAL | BID | BIK | BIN1 | BIN2 | BIN3 | BIN3-IT1 | Biogenesis of lysosome-related organelles complex-1 | BIRC2 | BIRC3 | BIRC5 | BIRC6 | BIRC7 | BIRC8 | BISPR | BIVM | BIVM-ERCC5 | BLACAT1 | BLACE | BLCAP | BLID | BLK | BLM | BLMH | BLNK | BLOC-1 (biogenesis of lysosome-related organelles complex 1) | BLOC1S1 | BLOC1S1-RDH5 | BLOC1S2 | BLOC1S3 | BLOC1S4 | BLOC1S5 | BLOC1S5-TXNDC5 | BLOC1S6 | BLTP1 | BLTP2 | BLTP3A | BLTP3B | BLVRA | BLVRB | BLZF1 | BMAL1 | BMAL2 | BMAL2-AS1 | BMERB1 | BMF | BMI1 | BMP1 | BMP10 | BMP15 | BMP2 | BMP2K | BMP3 | BMP4 | BMP5 | BMP6 | BMP7 | BMP8A