PRAMEF4: A Potential Drug Target and Biomarker (G400735)

Target Name: PRAMEF4

NCBI ID: G400735

Other Name(s): PRAME family member 4 | PRAM4_HUMAN | RP5-845O24.6

PRAMEF4: A Potential Drug Target and Biomarker

PRAMEF4, also known as PRAME family member 4, is a protein that is expressed in various tissues and cells throughout the body. It is a member of the PRAME family, which includes proteins that play a critical role in cell signaling and inflammation. PRAMEF4 has has been identified as a potential drug target and biomarker due to its unique structure and expression pattern in various tissues.

The PRAME family of proteins is characterized by the presence of a conserved domain that includes a N-terminal alpha-helix, a central beta-sheet, and a C-terminal terminal hypervariable region (TVR). This conserved domain is thought to be responsible for the unique structure and function of each member of the PRAME family. PRAMEF4 is no exception to this general rule, as it also contains a N-terminal alpha-helix, a central 尾-sheet, and a C-terminal TVR.

One of the key features of PRAMEF4 is its expression pattern. PRAMEF4 is highly expressed in various tissues, including brain, heart, and muscle. It is also expressed in various cell types, including neurons, endothelial cells, and immune cells. This broad expression pattern suggests that PRAMEF4 may be involved in a wide range of physiological processes in the body.

Another potential drug target for PRAMEF4 is its role in inflammation. PRAMEF4 has been shown to be involved in the regulation of inflammation and inflammation-related processes. For example, studies have shown that PRAMEF4 is involved in the regulation of pain signaling, and that it may play a role in the development of certain types of cancer.

In addition to its potential drug target and biomarker properties, PRAMEF4 also has interesting structural features that may make it a useful target for study. The N-terminal alpha-helix and the central 尾-sheet of PRAMEF4 are known to be involved in the regulation of protein function, and the C-terminal TVR is thought to be involved in the regulation of protein stability. This knowledge of protein structure and function may provide insights into the mechanisms of PRAMEF4's activity and its potential as a drug target.

Overall, PRAMEF4 is a protein that has a unique structure and expression pattern that makes it a potential drug target and biomarker. Its broad expression pattern and involvement in various physiological processes make it an attractive target for further study, and its interesting structural features may provide insight into its function in the body. Further research is needed to fully understand the potential of PRAMEF4 as a drug target and biomarker.

Protein Name: PRAME Family Member 4

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