Target Name: ETV7
NCBI ID: G51513
Other Name(s): Ets variant gene 7 (TEL2 oncogene) | ETS variant 7 | Tel-related Ets factor | TELB | ETS translocation variant 7 | Transcription factor Tel-2 | ets variant gene 7 (TEL2 oncogene) | ETS variant transcription factor 7, transcript variant 1 | ETV7_HUMAN | ETS variant transcription factor 7 | Ets transcription factor TEL-2b | TEL-2 | TEL2 oncogene | Transcription factor ets | Transcription factor ETV7 (isoform 1) | Transcription factor ETV7 | ETV7 variant 1 | ETS-related protein Tel2 | tel-related Ets factor | TEL2

ETV7: A Potential Cancer and Neuroscience Drug Target

ETV7 (Ets variant gene 7) is a gene that encodes a protein known as ETV7-TEL2, which is a transcription factor that plays a role in the development and maintenance of tissues such as brain, heart, and muscle. The ETV7 gene has been implicated in the development and progression of various diseases, including cancer.

One of the most significant aspects of the ETV7 gene is its role in cancer development. ETV7 has been shown to be highly expressed in a variety of cancer types, including lung, breast, and ovarian cancer. Additionally, studies have shown that inhibiting the activity of ETV7 can lead to the growth arrest and regression of cancer cells.

In addition to its role in cancer development, ETV7 has also been linked to a number of other cellular processes that are important for normal tissue growth and development. For example, ETV7 has been shown to play a role in the development and maintenance of neuronal cells, which are critical for the proper functioning of the nervous system.

Another promising aspect of the ETV7 gene is its potential as a drug target. By inhibiting the activity of ETV7, it is possible to reduce the growth and spread of cancer cells, which could be a key step in the development of more effective cancer treatments. Additionally, because ETV7 is involved in a number of important cellular processes that are necessary for normal tissue growth and development, it is possible that inhibiting its activity could have a broader range of potential applications in a variety of fields, including medicine, regenerative biology, and development.

In conclusion, ETV7 is a gene that has the potential to be a drug target or biomarker for a variety of diseases. Its role in cancer development and its involvement in the cellular processes that are necessary for normal tissue growth and development make it an attractive target for researchers and clinicians alike. Further research is needed to fully understand the mechanisms of its activity and its potential applications in medicine.

Protein Name: ETS Variant Transcription Factor 7

Functions: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity

More Common Targets

Eukaryotic translation initiation factor 2-alpha kinase | Eukaryotic translation initiation factor 2B | Eukaryotic translation initiation factor 3 (eIF-3) complex | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | Eukaryotic Translation Initiation Factor 4E Binding Protein | EVA1A | EVA1A-AS | EVA1B | EVA1C | EVC | EVC2 | EVI2A | EVI2B | EVI5 | EVI5L | EVL | EVPL | EVPLL | EVX1 | EVX1-AS | EVX2 | EWSAT1 | EWSR1 | EXD1 | EXD2 | EXD3 | EXO1 | EXO5 | EXOC1 | EXOC1L | EXOC2 | EXOC3 | EXOC3-AS1 | EXOC3L1 | EXOC3L2 | EXOC3L4 | EXOC4 | EXOC5 | EXOC5P1 | EXOC6 | EXOC6B | EXOC7 | EXOC8 | Exocyst complex | EXOG | EXOGP1 | Exon junction complex | EXOSC1 | EXOSC10 | EXOSC10-AS1 | EXOSC2 | EXOSC3 | EXOSC4 | EXOSC5 | EXOSC6 | EXOSC7 | EXOSC8 | EXOSC9 | Exosome Complex | EXPH5 | EXT1 | EXT2 | EXTL1 | EXTL2 | EXTL2P1 | EXTL3 | EXTL3-AS1 | EYA1 | EYA2 | EYA3 | EYA4 | EYS | EZH1 | EZH2 | EZHIP | EZR | F10 | F11 | F11-AS1 | F11R | F12 | F13A1 | F13B | F2 | F2R | F2RL1 | F2RL2 | F2RL3 | F3 | F5 | F7 | F8 | F8A1 | F8A2 | F8A3 | F9 | FA2H | FAAH | FAAH2 | FAAHP1