Target Name: TRMO
NCBI ID: G51531
Other Name(s): NAP1 | HSPC219 | Nef (lentivirus myristoylated factor) associated protein 1 | TRMO_HUMAN | TRNA methyltransferase O, transcript variant 1 | RP11-23B15.3 | TRNA (adenine(37)-N6)-methyltransferase (isoform 1) | tRNA (adenine(37)-N6)-methyltransferase | tRNA methyltransferase O | nef-associated protein 1 | Thioesterase NAP1 | TRMO variant 1 | Nef associated protein 1 | C9orf156 | thioesterase NAP1

TRMO: A Drug Target for Cancer

TRMO (Tumor Margin Enhancement) is a drug target (also known as biomarker) that is involved in cancer progression. It is a protein that is expressed in various tissues, including the brain, and has been shown to be involved in the development and progression of certain types of cancer.

One of the main functions of TRMO is its role in cell signaling. It is a transcription factor that is involved in the regulation of gene expression, and it has been shown to play a role in the development and progression of cancer.

In addition to its role in cell signaling, TRMO has also been shown to be involved in the formation of blood-brain barrier (BBB). The BBB is a barrier that separates the brain from the surrounding blood vessels, and it helps to protect the brain from the harmful effects of certain substances.

TRMO has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed in the body. This is important for the growth and progression of cancer, as cancer cells need access to oxygen and nutrients in order to grow and survive.

Another function of TRMO is its role in immune surveillance. It is a protein that is expressed in the immune system, and it has been shown to play a role in the immune response against cancer.

In conclusion, TRMO is a protein that is involved in various functions that are important for cancer progression. As a drug target, it has the potential to be used to treat a wide range of cancer types. Further research is needed to fully understand the role of TRMO in cancer, and to develop safe and effective treatments.

Protein Name: TRNA Methyltransferase O

Functions: S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) (PubMed:25063302). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability (By similarity)

More Common Targets

TRMT1 | TRMT10A | TRMT10B | TRMT10C | TRMT11 | TRMT112 | TRMT12 | TRMT13 | TRMT1L | TRMT2A | TRMT2B | TRMT44 | TRMT5 | TRMT6 | TRMT61A | TRMT61B | TRMT9B | TRMU | TRN-GTT4-1 | TRNA | tRNA splicing endonuclease complex | tRNA(Sec) complex | tRNA-splicing endonuclease complex | tRNA-splicing ligase complex | TRNAU1AP | TRNC | TRND | TRNE | TRNF | TRNG | TRNH | TRNI | TRNK | TRNL1 | TRNL2 | TRNM | TRNN | TRNP | TRNP1 | TRNQ | TRNR | TRNS1 | TRNS2 | TRNT | TRNT1 | TRNV | TRNW | TRNY | TRO | TROAP | TROAP-AS1 | Troponin | TRP-AGG2-5 | TRP-AGG6-1 | TRPA1 | TRPC1 | TRPC2 | TRPC3 | TRPC4 | TRPC4AP | TRPC5 | TRPC6 | TRPC7 | TRPC7-AS1 | TRPM1 | TRPM2 | TRPM2-AS | TRPM3 | TRPM4 | TRPM5 | TRPM6 | TRPM7 | TRPM8 | TRPS1 | TRPT1 | TRPV1 | TRPV2 | TRPV3 | TRPV4 | TRPV5 | TRPV6 | TRR-ACG1-2 | TRRAP | TRU-TCA2-1 | TRUB1 | TRUB2 | Trypanosome lytic factor 1 | Trypanosome lytic factor 2 | Trypsin | Tryptase | Tryptophan 5-Monooxygenase | TSACC | TSBP1 | TSBP1-AS1 | TSC1 | TSC2 | TSC22D1 | TSC22D1-AS1 | TSC22D2 | TSC22D3