FNDC8: A Promising Drug Target / Biomarker (G54752)

Target Name: FNDC8

NCBI ID: G54752

Other Name(s): Fibronectin type III domain containing 8 | Fibronectin type III domain-containing protein 8 | fibronectin type III domain containing 8 | FNDC8_HUMAN

FNDC8: A Promising Drug Target / Biomarker

Fused neurotransmitter release channels (FNDC8) are a family of proteins that play a crucial role in neurotransmitter release and signaling in the central nervous system (CNS). FNDC8 proteins are involved in the regulation of neurotransmitter release from various types of neurons, including dopamine, serotonin, and GABA. They are also involved in modulating the effects of neurotransmitters on target cells, including muscle cells and nerve cells.

FNDC8 is a protein that is expressed in many different types of neurons in the CNS, including those in the brainstem and spinal cord. It is involved in the regulation of neurotransmitter release from neurons and in modulating the effects of neurotransmitters on target cells. FNDC8 is a potential drug target and a biomarker for various neurological and psychiatric disorders, including depression, anxiety, and schizophrenia.

Purpose of the article

The purpose of this article is to provide an overview of FNDC8, including its structure, function, and potential as a drug target and biomarker. This will include an discussion of the current state of research on FNDC8 and its potential clinical applications.

Structure and function

FNDC8 is a protein that is characterized by a unique structure that consists of a long N-terminus, a transmembrane region, and a C-terminus. The N-terminus of FNDC8 is involved in the formation of a complex with other proteins, including the neurotransmitter acetylcholine. This complex is thought to play a role in modulating neurotransmitter release by affecting the strength of the acetylcholine-FNDC8 interaction.

The transmembrane region of FNDC8 is involved in the regulation of neurotransmitter release by affecting the trafficking of FNDC8 to the end of the neuron. The C-terminus of FNDC8 is involved in the regulation of neurotransmitter release by affecting the interaction between FNDC8 and the neurotransmitter transporter.

FNDC8 is involved in the regulation of neurotransmitter release from a variety of neurons, including those in the brainstem and spinal cord. It is thought to play a role in the regulation of neurotransmitter release from dopamine neurons, including the regulation of dopamine release in response to dopamine agonists.

FNDC8 is also involved in modulating the effects of neurotransmitters on target cells. It is thought to play a role in the regulation of neurotransmitter release from muscle cells, including the regulation of muscle tone. It is also involved in the regulation of neurotransmitter release from nerve cells, including the regulation of pain perception.

FNDC8 is a potential drug target and a biomarker for a variety of neurological and psychiatric disorders, including depression, anxiety, and schizophrenia. The regulation of neurotransmitter release by FNDC8 is thought to play a role in the pathophysiology of these disorders.

Current state of research

Current research on FNDC8 is focused on the regulation of neurotransmitter release by FNDC8. This is done through a variety of techniques, including biochemical, cellular, and animal models.

One of the most significant findings in research on FNDC8 is that it is involved in the regulation of neurotransmitter release from dopamine neurons. Studies have shown that FNDC8 plays a role in the regulation of dopamine release in response to dopamine agonists, including the regulation of dopamine release in the nucleus accumbens.

Another finding in research on FNDC8 is that it is involved in the regulation of neurotransmitter release from muscle cells. Studies have shown that FNDC8 plays a role in the regulation of muscle tone, including the regulation of muscle contractions.

FNDC8 is also involved in

Protein Name: Fibronectin Type III Domain Containing 8

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