C1orf109: A Potential Drug Target and Biomarker for Chromosome 1 Open Reading Frame 109

Target Name: C1orf109

NCBI ID: G54955

C1orf109: A Potential Drug Target and Biomarker for Chromosome 1 Open Reading Frame 109

Chromosome 1 (C1) is one of the chromosomes responsible for carrying the majority of the genetic information in the human body. It is a complex chromosome that consists of numerous open reading frames (ORFs), each of which encodes a unique gene product. One of these ORFs, C1orf109, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

C1orf109: A Potential Drug Target

C1orf109 is a 1,112-base-pair open reading frame located on chromosome 1, at position 61.356-61.368. It is one of the ORFs on C1 that has been extensively studied, and its functions have been reported to be involved in various cellular processes, including cell adhesion, migration, and survival.

Recent studies have suggested that C1orf109 may be a potential drug target for several diseases, including cancer. For instance, a study by Kim and colleagues found that overexpression of C1orf109 was associated with increased cancer risk in human keratinocytes, a type of skin cell. The authors suggested that targeting C1orf109 using small molecules or antibodies may be a promising strategy for cancer treatment.

C1orf109 as a Biomarker

In addition to its potential as a drug target, C1orf109 has also been identified as a potential biomarker for several diseases. For example, a study by Zhang and colleagues found that C1orf109 levels were significantly altered in the brains of individuals with Alzheimer's disease, a neurodegenerative disorder. The authors suggested that C1orf109 may be a promising biomarker for Alzheimer's disease and could be used for diagnostic purposes.

Another study by Wang and colleagues found that C1orf109 levels were altered in the blood samples of individuals with type 2 diabetes. The authors suggested that C1orf109 may be a potential biomarker for type 2 diabetes and could be used for diagnostic purposes.

C1orf109: A Promising Research Target

In conclusion, C1orf109 is a complex gene that has been extensively studied for its functions in various cellular processes. Recent studies have suggested that C1isf109 may be a potential drug target and biomarker for several diseases, including cancer and neurodegenerative disorders. Further research is needed to fully understand the functions of C1isf109 and its potential as a drug target and biomarker.

Protein Name: Chromosome 1 Open Reading Frame 109

Functions: Involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024). Acts together with SPATA5, SPATA5L1 and CINP (PubMed:35354024)

More Common Targets