AURKAIP1: A Potential Drug Target and Biomarker for Aurora-A Kinase Interaction

Target Name: AURKAIP1

NCBI ID: G54998

AURKAIP1: A Potential Drug Target and Biomarker for Aurora-A Kinase Interaction

Aurora-A kinase (Aurora-A) is a key enzyme involved in the control of cell proliferation and survival. The Aurora-A kinase is a protein that plays a crucial role in regulating cell cycle progression and apoptosis. It is composed of four subunits: A, B, C, and D. Aurora-A kinase is an essential protein for cell growth and development, and it is involved in many cellular processes, including cell division, apoptosis, and cell survival.

AURKAIP1 is a protein that interacts with Aurora-A kinase. It is a 21-kDa protein that is composed of 124 amino acid residues. AURKAIP1 is primarily localized to the endoplasmic reticulum (ER) and cytoplasm. It has been shown to interact with Aurora-A kinase, and this interaction is important for the function of Aurora-A kinase.

AURKAIP1 has been shown to play a critical role in the regulation of cell cycle progression and apoptosis. It is involved in the regulation of Aurora-A kinase activity, and it has been shown to inhibit the activity of Aurora-A kinase. This means that when Aurora-A kinase is activated, AURKAIP1 is able to inhibit its activity, thereby regulating cell cycle progression and apoptosis.

AURKAIP1 has also been shown to play a role in the regulation of cell survival. It is involved in the regulation of cell survival by controlling the apoptosis-associated protein (AP-1) expression. AP-1 is a protein that is involved in cell apoptosis, and it is composed of 41 amino acid residues. AURKAIP1 has been shown to interact with AP-1 and to regulate its expression. This means that when Aurora-A kinase is activated, AURKAIP1 is able to regulate the expression of AP-1, thereby controlling cell survival.

AURKAIP1 has been shown to play a critical role in the regulation of cellular processes, including cell growth, apoptosis, and cell survival. It is involved in the regulation of Aurora-A kinase activity, and it has been shown to inhibit the activity of Aurora-A kinase. This means that when Aurora-A kinase is activated, AURKAIP1 is able to inhibit its activity, thereby regulating cell cycle progression and apoptosis.

In conclusion, AURKAIP1 is a protein that interacts with Aurora-A kinase. It is a critical protein that plays a role in the regulation of cell cycle progression, apoptosis, and cell survival. AURKAIP1 has been shown to inhibit the activity of Aurora-A kinase, and this interaction is important for the function of Aurora-A kinase. Therefore, AURKAIP1 may be a potential drug target and biomarker for Aurora-A kinase interaction.

Protein Name: Aurora Kinase A Interacting Protein 1

Functions: May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation

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