BAIAP2L1: A Potential Drug Target and Biomarker for Cancer (G55971)
BAIAP2L1: A Potential Drug Target and Biomarker for Cancer
The protein Bar/IMD domain containing adapter protein 2 like 1 (BAIAP2L1) has been identified as a potential drug target and biomarker for the treatment of various diseases, including cancer. This protein plays a critical role in the inhibition of the tyrosine kinase Abl, which is a key regulator of cell growth and survival. TheBar/IMD domain containing adapter protein 2 like 1 (BAIAP2L1) has been shown to interact with the tyrosine kinase Abl and can inhibit its activity.
TheBAIAP2L1 is a member of the adapter protein family, which includes proteins that can interact with tyrosine kinase Abl and other tyrosine kinase, such as TP53 and kinase 12. TheBAIAP2L1 is unique in that it has a Bar/IMD domain, which is a conserved region that is found in proteins that interact with tyrosine kinase Abl. The Bar/IMD domain is known for its ability to interact with tyrosine kinase Abl and other tyrosine kinases, allowing it to modulate the activity of these enzymes.
TheBAIAP2L1 has been shown to play a critical role in the inhibition of tyrosine kinase Abl-mediated cell growth and survival. Studies have shown that theBAIAP2L1 can inhibit the activity of tyrosine kinase Abl with nanomoles of activity, which is equivalent to a 100% inhibition. This means that theBAIAP2L1 can effectively inhibit the activity of tyrosine kinase Abl, which is a key regulator of cell growth and survival.
In addition to its role in inhibiting tyrosine kinase Abl, theBAIAP2L1 has also been shown to interact with other proteins that are involved in cell signaling pathways. For example, theBAIAP2L1 has been shown to interact with the protein p53, which is a critical regulator of DNA repair and apoptosis. This interaction between theBAIAP2L1 and p53 suggests that theBAIAP2L1 may be involved in the regulation of cell apoptosis, which is a critical mechanism of disease progression.
TheBAIAP2L1 has also been shown to interact with the protein kinase 12, which is involved in cell signaling pathways. This interaction between theBAIAP2L1 and kinase 12 suggests that theBAIAP2L1 may be involved in the regulation of cell signaling pathways.
Due to its ability to inhibit tyrosine kinase Abl and interact with other proteins involved in cell signaling pathways, theBAIAP2L1 has potential as a drug target and biomarker for the treatment of various diseases, including cancer. Studies have shown that theBAIAP2L1 can be expressed and purified from Various cell lines, including cancer cells, and can be used for various assays, such as cell-based assays, protein-based assays, and assays of protein-protein interactions.
In conclusion, theBAIAP2L1 is a protein that has been shown to interact with tyrosine kinase Abl and other proteins involved in cell signaling pathways. Its ability to inhibit tyrosine kinase Abl and interact with other proteins suggests that it has potential as a drug target and biomarker for the treatment of various diseases, including cancer. Further studies are needed to fully understand the role of theBAIAP2L1 in cell signaling pathways and its potential as a drug target.
Protein Name: BAR/IMD Domain Containing Adaptor Protein 2 Like 1
Functions: May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection
More Common Targets
BAIAP2L2 | BAIAP3 | BAK1 | BALR6 | BAMBI | BANCR | BANF1 | BANF2 | BANK1 | BANP | BAP1 | BARD1 | BARHL1 | BARHL2 | BARX1 | BARX1-DT | BARX2 | BASC complex | BASP1 | BASP1-AS1 | BASP1P1 | BATF | BATF2 | BATF3 | BAX | BAZ1A | BAZ1A-AS1 | BAZ1B | BAZ2A | BAZ2B | BAZ2B-AS1 | BBC3 | BBIP1 | BBLN | BBOF1 | BBOX1 | BBOX1-AS1 | BBS1 | BBS10 | BBS12 | BBS2 | BBS4 | BBS5 | BBS7 | BBS9 | BBSome complex | BBX | BCAM | BCAN | BCAN-AS1 | BCAP29 | BCAP31 | BCAR1 | BCAR3 | BCAR3-AS1 | BCAR4 | BCAS1 | BCAS2 | BCAS2P2 | BCAS3 | BCAS4 | BCAT1 | BCAT2 | BCCIP | BCDIN3D | BCDIN3D-AS1 | BCHE | BCKDHA | BCKDHB | BCKDK | BCL10 | BCL10-AS1 | BCL11A | BCL11B | BCL2 | BCL2A1 | BCL2L1 | BCL2L10 | BCL2L11 | BCL2L12 | BCL2L13 | BCL2L14 | BCL2L15 | BCL2L2 | BCL2L2-PABPN1 | BCL3 | BCL6 | BCL6B | BCL7A | BCL7B | BCL7C | BCL9 | BCL9L | BCLAF1 | BCLAF3 | BCO1 | BCO2 | BCOR | BCORL1 | BCORP1