BCCIP: A Protein That Can Form A Covalent Complex with Inositol

Target Name: BCCIP

NCBI ID: G56647

BCCIP: A Protein That Can Form A Covalent Complex with Inositol

BCCIP (Beta-2-Cryoglobulin Inositol-Conjugated Protein) is a protein that is expressed in various tissues and cells in the body, including the liver, muscle, and heart. It is a member of the protein family of beta-globulins, which are a type of transmembrane protein that plays a variety of roles in cellular signaling and signaling pathways.

One of the unique features of BCCIP is its ability to form a covalent complex with inositol, a sugar molecule that is involved in various cellular signaling pathways. This complex is called the inositol-BCCIP complex and it plays a role in regulating cellular signaling pathways, including the intracellular signaling pathway, the cell signaling pathway, and the tissue signaling pathway.

In addition to its role in cellular signaling, BCCIP is also a potential drug target. Its ability to form a covalent complex with inositol makes it an attractive target for small molecules that can modulate its activity. This has led to a number of studies aimed at identifying and characterizing small molecules that can interact with BCCIP and modulate its activity.

One of the most promising small molecules that can interact with BCCIP is called N-(4-Mercaptoethoxy)benzamide (4-MEB). 4-MEB is a dietary supplement that is commonly used to support healthy brain function and has been shown to have a variety of neuroprotective effects.

4-MEB is able to form a covalent complex with BCCIP and modulate its activity in a number of ways. For example, 4-MEB has been shown to inhibit the activity of the protein tyrosine phosphatase, an enzyme that modulates the activity of BCCIP. This inhibition of tyrosine phosphatase activity allows 4-MEB to increase the activity of BCCIP, which in turn can modulate the activity of various cellular signaling pathways.

Another promising small molecule that can interact with BCCIP is called 2-Mercaptoethoxybenzamide (2-MEB). 2-MEB is a dietary supplement that is similar to 4-MEB, but with a different side chain. Like 4-MEB, 2-MEB is able to form a covalent complex with BCCIP and modulate its activity.

In addition to its potential use as a drug target, BCCIP is also a potential biomarker for a variety of diseases. Its ability to form a covalent complex with inositol makes it an attractive target for diagnostic tools that can detect changes in the level of BCCIP in the body. This has led to a number of studies aimed at identifying and characterizing small molecules that can interact with BCCIP and serve as biomarkers for disease.

Overall, BCCIP is a protein that is expressed in various tissues and cells in the body, and its unique ability to form a covalent complex with inositol makes it an attractive target for small molecules that can modulate its activity. While further research is needed to fully understand the role of BCCIP in cellular signaling and its potential as a drug target and biomarker, its properties and functions continue to be an important area of 鈥嬧?媟esearch in the field of molecular biology and biochemistry.

Protein Name: BRCA2 And CDKN1A Interacting Protein

Functions: During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole (PubMed:28394342). Isoform 2/alpha is particularly important for the regulation of microtubule anchoring, microtubule stability, spindle architecture and spindle orientation, compared to isoform 1/beta (PubMed:28394342). May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ)

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