BCL3: A Protein Target for Drug and Biomarker Development (G602)

Target Name: BCL3

NCBI ID: G602

BCL3: A Protein Target for Drug and Biomarker Development

BCL3 (Bcl-3 protein) is a protein that is expressed in a variety of tissues throughout the body, including the brain, lungs, heart, kidneys, and gastrointestinal tract. It is a member of the Bcl family of proteins, which are known for their ability to regulate cell death and cell survival.

The BCL3 protein is involved in a variety of physiological processes in the body, including cell signaling, DNA replication, and stress response. It has also been shown to play a role in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the most promising aspects of BCL3 is its potential as a drug target. BCL3 has been shown to be involved in a variety of cellular processes that are associated with the development and progression of disease, including cell signaling, angiogenesis, and inflammation. As such, it is a potential target for a variety of therapeutic approaches, including small molecule inhibitors, monoclonal antibodies, and adoptive T cell therapy.

In addition to its potential as a drug target, BCL3 is also a potential biomarker for a variety of diseases. Its expression has been shown to be associated with the development of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As such, BCL3 has the potential to be used as a biomarker for these diseases, and may be useful for the diagnosis and prognosis of these conditions.

The discovery and characterization of BCL3 as a potential drug target and biomarker is an exciting area of research, with implications for the treatment of a wide range of diseases. Further studies are needed to fully understand the role of BCL3 in disease and to develop effective therapies for the treatment of BCL3-related conditions.

Protein Name: BCL3 Transcription Coactivator

Functions: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity)

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