BCKDHB: A Protein Involved in Cell Adhesion and Migration (G594)

Target Name: BCKDHB

NCBI ID: G594

Other Name(s): dJ279A18.1 | E1B | dJ279A18.1 (branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)) | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | branched chain keto acid dehydrogenase E1, beta polypeptide | BCKDE1B | branched-chain alpha-keto acid dehydrogenase E1 component beta chain | BCKDHB variant 1 | branched chain alpha-ketoacid dehydrogenase E1-beta subunit | BCKDH E1-beta | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (isoform 1) | BCKDHB variant 2 | Branched chain keto acid dehydrogenase E1 subunit beta, transcript variant X1 | testis secretory sperm-binding protein Li 240mP | Branched chain keto acid dehydrogenase E1 subunit beta, transcript variant 1 | 2-oxoisovalerate dehydrogenase beta subunit | ODBB_HUMAN | branched chain keto acid dehydrogenase E1 beta | BCKDHB variant X1 | Branched chain keto acid dehydrogenase E1 subunit beta, transcript variant 2 | Branched-chain alpha-keto acid dehydrogenase E1 component beta chain | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial [Precursor] | branched chain keto acid dehydrogenase E1 subunit beta | E1b-beta subunit of the branched-chain complex

BCKDHB: A Protein Involved in Cell Adhesion and Migration

BCKDHB (beta-2-microglobulin), also known as dJ279A18.1, is a protein that is expressed in a variety of tissues throughout the body. It is a member of the beta-2 microglobulin family, which includes proteins that are involved in the regulation of cellular processes such as cell adhesion, migration, and invasion.

One of the key functions of BCKDHB is its role in cell adhesion. This protein helps to promote the stickiness of cells to other cells, allowing them to stick together and form tissues. This is important for many different processes in the body, including the development and maintenance of tissues such as skin, heart, and lungs.

Another important function of BCKDHB is its role in cell migration. This protein helps to regulate the movement of cells, allowing them to move to new locations in the body as needed. This is important for many different processes, including the formation of new tissues and organs during development.

In addition to its role in cell adhesion and migration, BCKDHB is also involved in the regulation of cell signaling pathways. This protein helps to regulate the signals that cells use to communicate with one another, allowing it to play a role in a variety of cellular processes.

Despite its many important functions, BCKDHB is not yet a well-established drug target. While there is some research being done to investigate the potential therapeutic uses of this protein, more research is needed to fully understand its role in the body and its potential as a drug target.

One potential way to target BCKDHB is through the use of small molecules. These molecules can be designed to interact with the protein in order to disrupt its function and prevent it from participating in cellular processes. This approach has been used to target many other proteins, and it may be a useful way to investigate the role of BCKDHB in the body.

Another potential approach to targeting BCKDHB is through the use of antibodies. These are proteins that are designed to recognize a specific protein, such as BCKDHB, and can be used to tag the protein for imaging or other purposes. This approach has been used to target many other proteins, and it may be a useful way to study the function of BCKDHB in the body.

Overall, BCKDHB is a protein that is involved in a variety of important cellular processes. While more research is needed to fully understand its role in the body, it may be a useful target for the development of new drugs for a variety of diseases.

Protein Name: Branched Chain Keto Acid Dehydrogenase E1 Subunit Beta

Functions: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3)

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