PRTFDC1: A Key Enzyme in Cellular Signaling Pathways (G56952)
PRTFDC1: A Key Enzyme in Cellular Signaling Pathways
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) is a protein that plays a crucial role in cellular signaling pathways. It is a key enzyme in the protein kinase CKL-dependent pathway, which is involved in a wide range of cellular processes, including cell growth , differentiation, and survival. PRTFDC1 is highly conserved across various species, and its structure and function have been extensively studied.
PRTFDC1 is a 21-kDa protein that consists of a catalytic domain and a 255-amino acid residue-containing non-catalytic region. The catalytic domain is the active site of the enzyme and is responsible for the transfer of phosphate groups to target proteins. The non-catalytic region is important for the regulation of the activity of the enzyme and for its stability.
PRTFDC1 is highly expressed in various tissues and cells, including the brain, heart, and pancreas. It is also involved in various cellular signaling pathways, including the regulation of cell growth, differentiation, and survival. One of the well-established functions of PRTFDC1 is its role in the regulation of cell survival. It has been shown to play a negative role in the regulation of cell survival and has been shown to be a potential drug target in various diseases.
PRTFDC1 has also been shown to be involved in the regulation of cell growth and differentiation. It has been shown to play a role in the regulation of cell proliferation and has been shown to be involved in the regulation of cell differentiation. to be involved in the regulation of cell migration and has been shown to play a role in the regulation of cell adhesion.
PRTFDC1 is also involved in the regulation of various cellular signaling pathways, including the regulation of cell adhesion, cell signaling pathways, and cell survival. It has been shown to play a role in the regulation of neurotransmitter signaling pathways, including the regulation of synaptic plasticity and the regulation of neurogenesis.
In conclusion, PRTFDC1 is a highly conserved protein that plays a crucial role in various cellular signaling pathways. Its function as a regulator of cell growth, differentiation, and survival makes it an attractive drug target for the development of new treatments for various diseases. Further research is needed to fully understand the role of PRTFDC1 in cellular signaling pathways and its potential as a drug target.
Protein Name: Phosphoribosyl Transferase Domain Containing 1
Functions: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage
More Common Targets
PRTG | PRTN3 | PRUNE1 | PRUNE2 | PRX | PRXL2A | PRXL2B | PRXL2C | PRY | PRY2 | PRYP3 | PRYP4 | PSAP | PSAPL1 | PSAT1 | PSAT1P1 | PSAT1P3 | PSCA | PSD | PSD2 | PSD3 | PSD4 | PSEN1 | PSEN2 | PSENEN | PSG1 | PSG10P | PSG11 | PSG2 | PSG3 | PSG4 | PSG5 | PSG6 | PSG7 | PSG8 | PSG9 | PSIP1 | PSKH1 | PSKH2 | PSMA1 | PSMA2 | PSMA3 | PSMA3-AS1 | PSMA3P1 | PSMA4 | PSMA5 | PSMA6 | PSMA7 | PSMA8 | PSMB1 | PSMB10 | PSMB11 | PSMB2 | PSMB3 | PSMB3P2 | PSMB4 | PSMB5 | PSMB6 | PSMB7 | PSMB7P1 | PSMB8 | PSMB8-AS1 | PSMB9 | PSMC1 | PSMC1P2 | PSMC1P4 | PSMC1P9 | PSMC2 | PSMC3 | PSMC3IP | PSMC4 | PSMC5 | PSMC6 | PSMD1 | PSMD10 | PSMD10P1 | PSMD11 | PSMD12 | PSMD13 | PSMD14 | PSMD2 | PSMD3 | PSMD4 | PSMD4P1 | PSMD5 | PSMD6 | PSMD6-AS2 | PSMD7 | PSMD8 | PSMD9 | PSME1 | PSME2 | PSME2P2 | PSME2P3 | PSME3 | PSME3IP1 | PSME4 | PSMF1 | PSMG1 | PSMG1-PSMG2 heterodimer