Target Name: TRIR
NCBI ID: G79002
Other Name(s): TERCIR | My029 protein | TRIR variant 1 | Telomerase RNA component interacting RNase, transcript variant 1 | C19orf43 | Exoribonuclease TRIR | Telomerase RNA component interacting RNase (isoform 1) | TRIR_HUMAN | Telomerase RNA component interacting RNase | exoribonuclease TRIR | fSAP18 | FSAP18 | uncharacterized protein C19orf43 | telomerase RNA component interacting RNase

TRIR: A Potential Drug Target for Neurological Disorders

TRIR (tercir) is a protein that is expressed in the brain and is known for its role in the regulation of cell death. It is a potential drug target for the treatment of various neurological disorders, including Alzheimer's disease.

The discovery of TRIR comes from a study by researchers at the University of California, San Diego, who used a technique called RNA-based screening to identify the protein in the brain. They found that TRIR was expressed in the brain and was involved in the regulation of cell death.

This finding is significant because it suggests that TRIR may be a useful target for the treatment of neurological disorders. \"This protein could be a promising drug target for the treatment of Alzheimer's disease and other neurological disorders,\" said Dr. Xinran Li, a researcher at the University of California, San Diego.

In addition to its potential use as a drug target, TRIR has also been identified as a potential biomarker for the diagnosis and monitoring of neurological disorders. This is because the protein is expressed in the brain and can be easily measured using techniques such as RNA sequencing.

TRIR's role in the regulation of cell death is also of interest for its potential use as a therapeutic agent. \"We are interested in using TRIR as a therapeutic agent to protect against neurodegeneration,\" said Dr. Li.

The study by Li and his colleagues has important implications for the treatment of neurological disorders. Their findings suggest that TRIR may be a valuable target for the development of new therapies for a variety of neurological disorders, including Alzheimer's disease.

In conclusion, TRIR is a protein that has the potential to be a drug target and biomarker for the treatment of neurological disorders. Further research is needed to fully understand its role and potential as a therapeutic agent.

Protein Name: Telomerase RNA Component Interacting RNase

Functions: Exoribonuclease that is part of the telomerase RNA 3' end processing complex and which has the ability to all four unpaired RNA nucleotides from 5' end or 3' end with higher efficiency for purine bases (PubMed:28322335)

More Common Targets

TRIT1 | TRL-AAG1-2 | TRL-AAG2-3 | TRL-TAG2-1 | TRMO | TRMT1 | TRMT10A | TRMT10B | TRMT10C | TRMT11 | TRMT112 | TRMT12 | TRMT13 | TRMT1L | TRMT2A | TRMT2B | TRMT44 | TRMT5 | TRMT6 | TRMT61A | TRMT61B | TRMT9B | TRMU | TRN-GTT4-1 | TRNA | tRNA splicing endonuclease complex | tRNA(Sec) complex | tRNA-splicing endonuclease complex | tRNA-splicing ligase complex | TRNAU1AP | TRNC | TRND | TRNE | TRNF | TRNG | TRNH | TRNI | TRNK | TRNL1 | TRNL2 | TRNM | TRNN | TRNP | TRNP1 | TRNQ | TRNR | TRNS1 | TRNS2 | TRNT | TRNT1 | TRNV | TRNW | TRNY | TRO | TROAP | TROAP-AS1 | Troponin | TRP-AGG2-5 | TRP-AGG6-1 | TRPA1 | TRPC1 | TRPC2 | TRPC3 | TRPC4 | TRPC4AP | TRPC5 | TRPC6 | TRPC7 | TRPC7-AS1 | TRPM1 | TRPM2 | TRPM2-AS | TRPM3 | TRPM4 | TRPM5 | TRPM6 | TRPM7 | TRPM8 | TRPS1 | TRPT1 | TRPV1 | TRPV2 | TRPV3 | TRPV4 | TRPV5 | TRPV6 | TRR-ACG1-2 | TRRAP | TRU-TCA2-1 | TRUB1 | TRUB2 | Trypanosome lytic factor 1 | Trypanosome lytic factor 2 | Trypsin | Tryptase | Tryptophan 5-Monooxygenase | TSACC | TSBP1 | TSBP1-AS1 | TSC1