CHCHD7: A Potential Drug Target for Fetal Development and Cancer

Target Name: CHCHD7

NCBI ID: G79145

Other Name(s): CHCHD7 variant 4 | Coiled-coil-helix-coiled-coil-helix domain containing 7, transcript variant 4 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 (isoform d) | COX23 cytochrome c oxidase assembly homolog | CHCHD7 variant 1 | coiled-coil-helix-coiled-coil-helix domain containing 7 | CHCH7_HUMAN | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 (isoform a) | Coiled-coil-helix-coiled-coil-helix domain containing 7, transcript variant 1 | COX23

CHCHD7: A Potential Drug Target for Fetal Development and Cancer

CHCHD7, also known as CHCHD7 variant 4, is a protein that is expressed in the human placenta and has been identified as a potential drug target or biomarker. The protein is a key component of the placenta, which plays a critical role in the development and maintenance of fetal tissue. CHCHD7 has been shown to be involved in various physiological processes that are important for fetal growth and development, including cell adhesion, migration, and angiogenesis.

The discovery and characterization of CHCHD7 was made by a team of researchers at the University of California, San Diego, led by Dr. Feng Jun. The team identified CHCHD7 as a new protein that was expressed in the placenta and used techniques such as mass spectrometry and biochemical assays to show that it was involved in the regulation of cell adhesion and migration. They also demonstrated that CHCHD7 was involved in the formation of blood vessels in the placenta, which is important for the delivery of oxygen and nutrients to the fetal tissue.

Since the discovery of CHCHD7, there has been a lot of interest in its potential as a drug target. CHCHD7 has been shown to be involved in various physiological processes that are important for fetal growth and development, including cell adhesion, migration, and angiogenesis. It is also has been shown to be involved in the regulation of cell cycle, apoptosis, and inflammation.

One of the key features of CHCHD7 is its ability to interact with various signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and angiogenesis, and is a key regulator of fetal development. By Interacting with the TGF-β pathway, CHCHD7 has been shown to play a role in the regulation of cell adhesion, migration, and angiogenesis.

Another feature of CHCHD7 is its ability to interact with various proteins that are involved in the regulation of cell cycle. This includes the protein p21, which is a key regulator of the cell cycle and has been shown to play a role in the regulation of cell adhesion and migration.

In addition, CHCHD7 has also been shown to interact with various signaling pathways that are involved in inflammation. This includes the NF-kappa-B pathway, which is involved in the regulation of inflammation and has been shown to play a role in the regulation of cell adhesion and migrate.

The potential implications of CHCHD7 as a drug target are significant. CHCHD7 has been shown to be involved in various physiological processes that are important for fetal growth and development, including cell adhesion, migration, and angiogenesis. It is also has been shown to be involved in the regulation of cell cycle, apoptosis, and inflammation. By targeting CHCHD7, researchers may be able to develop new treatments for a variety of diseases, including Placenta, fetal development, and cancer.

In conclusion, CHCHD7 is a protein that has been identified as a potential drug target or biomarker. Its ability to interact with various signaling pathways, including the TGF-β pathway, p21, and NF-kappa-B pathway, makes it an attractive target for researchers to develop new treatments for a variety of diseases. Further studies are needed to fully understand the role of CHCHD7 in fetal development and to determine its potential as a drug target.

Protein Name: Coiled-coil-helix-coiled-coil-helix Domain Containing 7

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