MANea: A Review on a Potential Drug Target and Biomarker (G79694)

Target Name: MANEA

NCBI ID: G79694

MANea: A Review on a Potential Drug Target and Biomarker

Introduction

Manea is a plant-based alkaloid that has been found to have various biological and pharmacological effects. It is a versatile compound that has been isolated from various plants and has been shown to be capable of modulating various cellular processes. MANea has been identified as a potential drug target and biomarker due to its unique chemical structure and biological activity.

Drug Target

MANea has been shown to interact with several protein kinases, including casein kinase 2 (CK-2), which is a key enzyme involved in cell signaling pathways. It has been shown to inhibit the activity of CK-2, leading to the inhibition of cell proliferation and the inhibition of the formation of blood vessels, which are potential drug targets for MANea.

Biomarker

MANea has also been shown to be involved in the regulation of various cellular processes, including cell pathways, which makes it an attractive signaling biomarker for drug development. For example, it has been shown to regulate the activity of the protein kinase B-catenin, which is involved in cell signaling pathways.

Compound Synthesis

MANea can be synthesized using various methods, including the synthesis of its 6-beta-carboxy-7-methoxy-1,2-dihydro-4H-pyran-2-one (1,2-dihydro-4H-pyran-2-one ) using various amino acids. The synthesis of MANea can also be done using various organic synthesis routes.

Pharmacological Evaluating

MANea has been shown to have various pharmacological effects, including the inhibition of cell proliferation and the inhibition of the formation of blood vessels. It has also been shown to have neuroprotective effects, such as the inhibition of oxidative stress and the inhibition of neuroinflammation.

Drug Development

MANea has been identified as a potential drug target due to its unique chemical structure and biological activity. The inhibition of CK-2 and the regulation of cellular processes make it an attractive drug candidate for the treatment of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

Conclusion

In conclusion, MANea is a versatile compound that has been shown to have various biological and pharmacological effects. Its unique chemical structure and its interaction with protein kinase make it an attractive drug target and biomarker. Further studies are needed to fully understand the potential of MANea as a drug.

Protein Name: Mannosidase Endo-alpha

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