Target Name: MAP2
NCBI ID: G4133
Other Name(s): Microtubule-associated protein 2 | MAP-2 | DKFZp686I2148 | MAP2B | MAP2C | MTAP2_HUMAN | Microtubule-associated protein 2 (isoform 1) | MAP2A | OTTHUMP00000163916 | microtubule associated protein 2 | Microtubule associated protein 2, transcript variant 1 | MAP2 variant 1

MAP2: A Potential Drug Target and Biomarker

MAP2 (Microtubule-associated protein 2) is a protein that is expressed in various tissues throughout the body, including muscle, brain, and organs. It is a member of the microtubule protein family, which plays a critical role in the structure and function of mitotic organizing organelles in eukaryotic cells.

MAP2 is a 21-kDa protein that is expressed in a variety of tissues, including muscle, brain, heart, and organs. It is highly conserved across different species, and its only conserved amino acid residue is Asp212. MAP2 is localized to the microtubules, where it plays a structural role in the organization of the microtubules.

MAP2 is involved in many different cellular processes in eukaryotic cells, including cell division, intracellular transport, and cell signaling. It is a key regulator of mitotic organizing in eukaryotic cells, and is required for the proper formation and maintenance of microtubules.

MAP2 is a potential drug target in the treatment of various diseases, including cancer, neurodegenerative diseases, and developmental disorders. Its involvement in cell signaling and division makes it an attractive target for small molecules that can inhibit its activity.

MAP2 is also a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and developmental disorders. Its expression is often reduced in cancer cells, and its levels are elevated in neurodegenerative diseases. This makes it an potential indicator of disease severity and a target for therapeutic intervention.

MAP2 is a complex protein that is expressed in a variety of tissues throughout the body. Its only conserved amino acid residue is Asp212, and it is localized to the microtubules where it plays a critical role in the organization of the microtubules. MAP2 is involved in many different cellular processes in eukaryotic cells, including cell division, intracellular transport, and cell signaling. It is a key regulator of mitotic organizing in eukaryotic cells, and is required for the proper formation and maintenance of microtubules.

MAP2 is a potential drug target in the treatment of various diseases, including cancer, neurodegenerative diseases, and developmental disorders. Its involvement in cell signaling and division makes it an attractive target for small molecules that can inhibit its activity.

MAP2 is also a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and developmental disorders. Its expression is often reduced in cancer cells, and its levels are elevated in neurodegenerative diseases. This makes it an potential indicator of disease severity and a target for therapeutic intervention.

In conclusion, MAP2 is a protein that is expressed in various tissues throughout the body, including muscle, brain, and organs. It is a member of the microtubule protein family and plays a critical role in the structure and function of mitotic organizing organelles in eukaryotic cells. As a result, MAP2 is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand its role in cellular processes and its potential as a therapeutic intervention.

Protein Name: Microtubule Associated Protein 2

Functions: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules

More Common Targets

MAP2K1 | MAP2K1P1 | MAP2K2 | MAP2K3 | MAP2K4 | MAP2K4P1 | MAP2K5 | MAP2K6 | MAP2K7 | MAP3K1 | MAP3K10 | MAP3K11 | MAP3K12 | MAP3K13 | MAP3K14 | MAP3K14-AS1 | MAP3K15 | MAP3K19 | MAP3K2 | MAP3K2-DT | MAP3K20 | MAP3K20-AS1 | MAP3K21 | MAP3K3 | MAP3K4 | MAP3K5 | MAP3K5-AS2 | MAP3K6 | MAP3K7 | MAP3K7CL | MAP3K8 | MAP3K9 | MAP3K9-DT | MAP4 | MAP4K1 | MAP4K1-AS1 | MAP4K2 | MAP4K3 | MAP4K3-DT | MAP4K4 | MAP4K5 | MAP6 | MAP6D1 | MAP7 | MAP7D1 | MAP7D2 | MAP7D3 | MAP9 | MAPK1 | MAPK10 | MAPK10-AS1 | MAPK11 | MAPK12 | MAPK13 | MAPK14 | MAPK15 | MAPK1IP1L | MAPK3 | MAPK4 | MAPK6 | MAPK6P2 | MAPK7 | MAPK8 | MAPK8IP1 | MAPK8IP1P2 | MAPK8IP2 | MAPK8IP3 | MAPK9 | MAPKAP1 | MAPKAPK2 | MAPKAPK3 | MAPKAPK5 | MAPKAPK5-AS1 | MAPKBP1 | MAPRE1 | MAPRE1P2 | MAPRE2 | MAPRE3 | MAPT | MAPT-AS1 | MAPT-IT1 | MARCHF1 | MARCHF10 | MARCHF11 | MARCHF11-DT | MARCHF2 | MARCHF3 | MARCHF4 | MARCHF5 | MARCHF6 | MARCHF6-DT | MARCHF7 | MARCHF8 | MARCHF9 | MARCKS | MARCKSL1 | MARCO | MARF1 | MARK1 | MARK2