MARCHF11: A Potential Drug Target Or Biomarker (G441061)
MARCHF11: A Potential Drug Target Or Biomarker
MARCHF11, also known as MARHB-HUMAN, is a protein that is expressed in human tissues and has been identified as a potential drug target or biomarker. The protein is derived from the Marrow-derived hematopoietic stem cell (HSC) and is expressed in various tissues, including the brain, spleen, and peripheral blood.
MARCHF11 is a transmembrane protein that is characterized by its extracellular domain, which is composed of a catalytic tyrosine kinase domain and a transmembrane region. The protein is involved in various cellular processes, including cell signaling, cell adhesion, and inflammation.
One of the key functions of MARCHF11 is its role in the regulation of cell proliferation. The protein is known to play a role in the G1/S transition, which is the process by which cells prepare for cell division. During the G1/S transition, MARCHF11 is involved in the regulation of the expression of genes that are involved in cell growth and differentiation.
Another function of MARCHF11 is its role in cell adhesion. The protein is known to be involved in the regulation of cell-cell adhesion, which is the process by which cells stick together to form tissues. This function is important for the development and maintenance of tissues and organs, as well as for the regulation of various diseases, such as cancer.
MARCHF11 is also involved in the regulation of inflammation. The protein is known to be involved in the regulation of the immune response, as well as the regulation of inflammation. This is important for the regulation of various diseases, such as autoimmune diseases and inflammatory bowel disease.
Due to its involvement in these cellular processes, MARCHF11 has been identified as a potential drug target or biomarker. The protein is also a good candidate for a diagnostic marker for various diseases, such as cancer, due to its expression in various tissues and its potential role in the regulation of cellular processes.
In conclusion, MARCHF11 is a protein that is expressed in human tissues and has been identified as a potential drug target or biomarker. The protein is involved in various cellular processes, including cell signaling, cell adhesion, and inflammation, and has been shown to play a role in the regulation of cell proliferation, adhesion, and the immune response. Further research is needed to fully understand the role of MARCHF11 in these processes and its potential as a drug target or biomarker.
Protein Name: Membrane Associated Ring-CH-type Finger 11
Functions: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids
More Common Targets
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