MATN1-AS1: A Potential Drug Target and Biomarker (G100129196)

Target Name: MATN1-AS1

NCBI ID: G100129196

Other Name(s): MATN1 antisense RNA 1

MATN1-AS1: A Potential Drug Target and Biomarker

MATN1-AS1 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the matrixin-related proteins (MAT) family, which are known for their role in cell-cell adhesion, migration, and invasion. MATN1-AS1 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, it has become an attractive target for drug development.

The discovery and characterization of MATN1-AS1

The MATN1-AS1 gene was first identified in the late 1990s using DNA-based studies. The gene is located on chromosome 6p and has a single exon. The protein that MATN1-AS1 encodes is a 21 kDa protein that contains 10 transmembrane domains and a N-terminus.

Expression of MATN1-AS1 is highly specific to various tissues and organs, including the brain, heart, and kidneys. It is expressed in the brain at levels of 1-2% of the total protein in the brain and is highly expressed in the heart and kidneys. MATN1-AS1 is also expressed in various other tissues, including the liver, pancreas, and gastrointestinal tract.

Function and localization of MATN1-AS1

MATN1-AS1 is involved in several cellular processes that are important for normal tissue growth and development. One of its functions is to regulate the actin cytoskeleton, which is responsible for the structural integrity of cells. MATN1-AS1 is known to play a role in the regulation of actin dynamics and in the assembly of actin-associated protein 2 (AAP2).

MATN1-AS1 is also involved in the regulation of cell-cell adhesion and migration. It has been shown to play a role in the regulation of tight junction formation and in the inhibition of cell migration. MATN1-AS1 has also been shown to play a role in the regulation of neuronal excitability and synaptic plasticity.

MATN1-AS1 is also involved in the regulation of inflammation and immune responses. It has been shown to play a role in the regulation of cytokine production and in the modulation of immune cell function. MATN1-AS1 has also been shown to play a role in the regulation of pain perception and neuroinflammation.

Drug targeting MATN1-AS1

Drug targeting MATN1-AS1 is an attractive approach for the development of new treatments for various diseases. MATN1-AS1 has been shown to play a role in the development and progression of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One potential approach to drug targeting MATN1-AS1 is to use small molecules that can inhibit its activity. Several studies have shown that inhibitors of MATN1-AS1 have the potential to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Another potential approach to drug targeting MATN1-AS1 is to use antibodies that can specifically recognize and target its N-terminus. Several studies have shown that antibodies that can specifically recognize and target MATN1-AS1 N-terminus have the potential to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Conclusion

MATN1-AS1 is a protein that is involved in several cellular processes that are important for normal tissue growth and development. Its functions include

Protein Name: MATN1 Antisense RNA 1

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