MC5R: A Protein Involved in Cell Biology and Disease (G4161)

MC5R: A Protein Involved in Cell Biology and Disease

MC5R (Mesothelin Carboxylic Acid Receptor) is a protein that is expressed in various tissues throughout the body, including the skin, heart, lungs, and brain. It is a transmembrane glycoprotein that is involved in cell-cell adhesion, migration, and invasion. It is also a potential drug target and biomarker for various diseases, including cancer, cardiovascular disease, and neurological disorders.

MC5R is composed of a extracellular domain, a transmembrane region, and an intracellular domain. The extracellular domain is responsible for the protein's ability to interact with cell surface receptors and other proteins. The transmembrane region is responsible for the protein's ability to span the cell membrane and interact with intracellular signaling pathways. The intracellular domain is responsible for the protein's ability to interact with other proteins inside the cell.

MC5R has been shown to play a role in various physiological processes in the body, including cell growth, differentiation, and migration. It is involved in the regulation of cell-cell adhesion, which is critical for the development and maintenance of tissues and organs. MC5R is also involved in the regulation of cell migration, which is essential for the formation of tissues and organs during development and wound healing.

In addition to its role in cell biology, MC5R is also a potential drug target and biomarker for various diseases. For example, MC5R has been shown to be overexpressed in various types of cancer, including breast, lung, and ovarian cancer. This suggests that targeting MC5R with drugs that can inhibit its function may be an effective way to treat these diseases.

MC5R has also been shown to be involved in the regulation of various signaling pathways in the body. For example, it is involved in the regulation of the TGF-β pathway, which is a critical signaling pathway involved in the development and maintenance of tissues and organs. Additionally, MC5R is involved in the regulation of the Wnt pathway, which is involved in the development and maintenance of tissues and organs during development and embryonic development.

MC5R is also a potential biomarker for various diseases, including cancer. This is because it is often overexpressed in cancer tissues and can be used as a target for drugs that can inhibit its function. For example, studies have shown that targeting MC5R with drugs that can inhibit its function may be an effective way to treat various types of cancer, including breast, lung, and ovarian cancer.

In conclusion, MC5R is a protein that is involved in various physiological processes in the body, including cell growth, differentiation, and migration. It is also a potential drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand the role of MC5R in these processes and to develop effective treatments for these diseases.

Protein Name: Melanocortin 5 Receptor

Functions: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins

More Common Targets

MCAM | MCAT | MCC | MCCC1 | MCCC2 | MCCD1 | MCCD1P1 | MCEE | MCEMP1 | MCF2 | MCF2L | MCF2L-AS1 | MCF2L2 | MCFD2 | MCFD2P1 | MCHR1 | MCHR2 | MCHR2-AS1 | MCIDAS | MCL1 | MCM10 | MCM2 | MCM3 | MCM3AP | MCM3AP-AS1 | MCM4 | MCM5 | MCM6 | MCM7 | MCM8 | MCM8-MCM9 complex | MCM9 | MCMBP | MCMDC2 | MCOLN1 | MCOLN2 | MCOLN3 | MCPH1 | MCPH1-AS1 | MCPH1-DT | MCRIP1 | MCRIP2 | MCRS1 | MCTP1 | MCTP2 | MCTS1 | MCTS2 | MCU | MCUB | MCUR1 | MDC1 | MDFI | MDFIC | MDGA1 | MDGA2 | MDH1 | MDH1B | MDH2 | MDK | MDM1 | MDM2 | MDM4 | MDN1 | MDS2 | ME1 | ME2 | ME3 | MEA1 | MEAF6 | MEAF6P1 | MEAK7 | Mechanoelectrical transducer (MET) channel | Mechanosensitive Ion Channel | MECOM | MECOM-AS1 | MeCP1 histone deacetylase (HDAC) complex | MECP2 | MECR | MED1 | MED10 | MED11 | MED12 | MED12L | MED13 | MED13L | MED14 | MED14P1 | MED15 | MED15P8 | MED16 | MED17 | MED18 | MED19 | MED20 | MED21 | MED22 | MED23 | MED24 | MED25 | MED26