Target Name: MCCC1
NCBI ID: G56922
Other Name(s): MCCase subunit alpha | 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha | Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (isoform 1) | MCCC1 variant 1 | MCCA | methylcrotonoyl-CoA carboxylase 1 (alpha) | 3-Methylcrotonyl-CoA carboxylase biotin-containing subunit | methylcrotonoyl-CoA carboxylase alpha | MCCase alpha subunit | Methylcrotonyl-CoA carboxylase subunit 1, transcript variant 1 | 3-methylcrotonyl-CoA carboxylase biotin-containing subunit | Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial | MCC-B | 3-Methylcrotonyl-CoA:carbon dioxide ligase alpha subunit | MCCCalpha | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | methylcrotonyl-CoA carboxylase subunit 1 | 3-methylcrotonyl-CoA carboxylase 1 | MCCA_HUMAN

MCCC1: A Potential Drug Target Or Biomarker

MCCC1 (MCCase subunit alpha), a protein that belongs to the MCC family, plays a critical role in various cellular processes. MCCs are known for their ability to interact with other proteins and molecules, which allows them to participate in a wide range of cellular functions. MCCC1 is one of the MCC proteins that has been identified as a potential drug target or biomarker.

The MCC family of proteins consists of different subunits, including MCC1, MCC2, MCC3, and MCC4. These subunits share a conserved catalytic core and share similar structural features. MCC1 is a 14-kDa protein that is expressed in various tissues, including brain, heart, and muscle. It is involved in the regulation of cellular processes such as cell adhesion, migration, and invasion.

MCCC1 is a key protein that is involved in the regulation of cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs. MCCC1 plays a critical role in the regulation of cell-cell adhesion by interacting with various adhesion molecules, including cadherins and immunoglobulin-like cell adhesion molecules (Ig-CAMs).

MCCC1 is also involved in the regulation of cell migration and invasion. During cell division, MCCC1 helps to ensure that the dividing cells stick together and divide correctly. It also plays a role in the migration of cells towards new environments, such as when cells invade a new tissue.

In addition to its role in cell adhesion and migration, MCCC1 is also involved in the regulation of cell survival. Studies have shown that MCCC1 can interact with various stress signaling pathways, including the p53 pathway. This suggests that MCCC1 may be involved in the regulation of cellular stress responses, which could potentially lead to the development of cancer.

MCCC1 is also a potential biomarker for various diseases. For example, MCCC1 has been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Studies have also shown that MCCC1 may be involved in the development of certain cancers, such as breast and ovarian cancer.

In conclusion, MCCC1 is a protein that plays a critical role in various cellular processes. Its involvement in cell adhesion, migration, and invasion, as well as its potential involvement in stress signaling pathways and cancer development, makes it an attractive target for research and potential therapeutic intervention. Further studies are needed to fully understand the role of MCCC1 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Methylcrotonyl-CoA Carboxylase Subunit 1

Functions: Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism

More Common Targets

MCCC2 | MCCD1 | MCCD1P1 | MCEE | MCEMP1 | MCF2 | MCF2L | MCF2L-AS1 | MCF2L2 | MCFD2 | MCFD2P1 | MCHR1 | MCHR2 | MCHR2-AS1 | MCIDAS | MCL1 | MCM10 | MCM2 | MCM3 | MCM3AP | MCM3AP-AS1 | MCM4 | MCM5 | MCM6 | MCM7 | MCM8 | MCM8-MCM9 complex | MCM9 | MCMBP | MCMDC2 | MCOLN1 | MCOLN2 | MCOLN3 | MCPH1 | MCPH1-AS1 | MCPH1-DT | MCRIP1 | MCRIP2 | MCRS1 | MCTP1 | MCTP2 | MCTS1 | MCTS2 | MCU | MCUB | MCUR1 | MDC1 | MDFI | MDFIC | MDGA1 | MDGA2 | MDH1 | MDH1B | MDH2 | MDK | MDM1 | MDM2 | MDM4 | MDN1 | MDS2 | ME1 | ME2 | ME3 | MEA1 | MEAF6 | MEAF6P1 | MEAK7 | Mechanoelectrical transducer (MET) channel | Mechanosensitive Ion Channel | MECOM | MECOM-AS1 | MeCP1 histone deacetylase (HDAC) complex | MECP2 | MECR | MED1 | MED10 | MED11 | MED12 | MED12L | MED13 | MED13L | MED14 | MED14P1 | MED15 | MED15P8 | MED16 | MED17 | MED18 | MED19 | MED20 | MED21 | MED22 | MED23 | MED24 | MED25 | MED26 | MED27 | MED28 | MED29 | MED30